Theses - Veterinary Medicine: Recent submissions
Now showing items 1-4 of 50
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Development and validation of a CRISPR interference system for gene regulation in Campylobacter jejuni
Campylobacter spp. are the leading cause of bacterial food-borne illness in humans worldwide, with Campylobacter jejuni responsible for 80% of these infections. There is an urgent need to understand fundamental C. jejuni ... -
Genomic insights into the host range and interspecies transmission dynamics of Staphylococcus aureus
(2022-01-18)Staphylococcus aureus is an important human bacterial pathogen with a wide host range, including livestock, companion, and wild animal species. Genomic and epidemiological studies show that S. aureus can freely transmit ... -
Genetics of transmissible cancers in the Tasmanian devil (Sarcophilus harrisii)
Transmissible cancers are clonal lineages that spread through populations via contagious cancer cells. Such epidemics have only ever been observed to affect two mammals in nature, yet two distinct clones known as devil ... -
Understanding the mechanisms of phosphatidylserine exposure in sickle cells
Sickle cell disease (SCD) is the most common severe inherited disorder affecting millions of people worldwide. HbS polymerisation leads to a change in red blood cells’ (RBCs) membrane permeability, high phosphatidylserine ...