Theses - MRC Laboratory of Molecular Biology
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The elucidation of immunological and oncological transcriptomic signatures using translational ontologies and next-generation sequencing (MRC Laboratory of Molecular Biology, University of Cambridge, 2014-10-07)Understanding the large amounts of information produced by next-generation sequencing requires the comprehensive integration of biological knowledge, appropriate statistical frameworks, and computational models. In this ...
(2008-10-14)The Microtubule (MT) network is a central component of the eukaryotic cell cytoskeleton. In the fission yeast S. pombe, a complex of three proteins specifically tracks MT +ends and stabilizes MTs in the cell. It is composed ...
Biochemical and structural studies of the FtsZ:FtsA complex and polymerising abilities of the FtsA protein (2012-04-10)A key step in bacterial cell division is the formation of the Z-ring composed of polymers of the tubulin-like protein FtsZ. The Z-ring constricts and through interaction with other components engages in remodelling the ...