European Bioinformatics Institute (EMBL-EBI): Recent submissions
Now showing items 5-8 of 41
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Understanding the genetics and function of complex human retinal phenotypes
The human retina is the tissue at the back of the eye responsible for converting light stimulus into neuronal signal that can be interpreted by the brain. To perform this integral role within the central nervous system, ... -
Using single-cell RNA-seq to assess the effect of common genetic variants on gene expression during development
Over the last fifteen years, genome-wide association studies (GWAS) have been used to identify thousands of DNA variants associated with complex traits and diseases, by exploiting naturally occurring genetic variation in ... -
Mapping the Genomic Context of Mutagenesis
(2020-11-30)The accumulation of genomic mutations leads to the formation of cancer. For this reason, many efforts have been undertaken to characterise mutational processes in terms of their genomic imprints. A particularly successful ... -
Statistical methods for the integrative analysis of single-cell multi-omics data
Single-cell profiling techniques have provided an unprecedented opportunity to study cellular heterogeneity at the molecular level. This represents a remarkable advance over traditional bulk sequencing methods, particularly ...
