European Bioinformatics Institute (EMBL-EBI): Recent submissions
Now showing items 5-8 of 47
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Statistical analysis of short template switch mutations in human genomes
Many complex rearrangements arise in human genomes through template switch mutations, which occur during DNA replication when there is a transient polymerase switch to an alternate template nearby in three-dimensional ... -
Examining bacterial variation with genome graphs and Nanopore sequencing
A bacterial species' genetic content can be remarkably fluid. The collection of genes found within a given species is called the pan-genome and is generally much larger than the gene repertoire of a single cell. A consequence ... -
DNA Phonology: Investigating the Codon Space
(2003-11-04)The main part of the thesis is concerned with large-scale studies of codon usage in completely sequenced genomes. A new compositional analysis scheme is presented, complete with a number of computation and visualisation ... -
Insights into transcriptional regulation from natural and induced variation in closely related species
Despite years of research, numerous aspects of gene regulatory mechanisms and their contributions to shaping phenotypic characteristics remain elusive. In this thesis, I gain insights into mechanisms of transcriptional ...
