Theses - Pharmacology
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Recent Submissions
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Rational development of novel small molecule leads against the transcriptional activator protein ExsA of Pseudomonas aeruginosa
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen. It is present in aquatic, marine, and soil environments and can also be found in a variety of anthropological environments, including water distribution ... -
Investigating novel therapeutic targets for treatment of visceral pain.
Abdominal pain is a common symptom of gastrointestinal disorders such as Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). However, despite the many treatments for inflammation in IBD and disordered ... -
Development and experimental validation of a novel arterial thrombosis-on-a-chip microfluidic device
Cardiovascular disease remains one of the world’s leading causes of death. Myocardial infarction (heart attack) is triggered by occlusion of coronary arteries by platelet-rich thrombi (clots). The development of new ... -
Angiotensin II signalling in sensory neurons
Angiotensin II (Ang II) is a peptide associated with the regulation of blood pressure, though the elevated presence of Ang II in the inflamed bowel – and other inflamed tissues – and the presence of receptors for Ang II ...
