Theses - Pharmacology
About this collection
Recent Submissions
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On the mechanisms of transport and energy coupling in ABC exporters
(2018-07-21)The rapid emergence of multidrug resistant bacterial strains represents a major global healthcare issue. Amongst five known classes of membrane transporters, which play a huge role in multidrug efflux, primary-active ... -
DNA double-strand break repair studied by atomic force microscopy
(2018-07-20)DNA double-strand breaks (DSBs), where both strands of the DNA duplex are simultaneously fractured, are considered the most lethal type of DNA damage. The conserved Mre11-Rad50 DNA repair complex enables the catalytic ... -
Investigating the Non-globular Proteins of the Canonical Wnt Signalling Pathway
(2018-06-29)The canonical Wnt pathway is a vitally important signalling pathway that plays an important role in cell proliferation, differentiation and fate decisions in embryonic development and in the maintenance of adult tissues. ...
