Theses - Pharmacology
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The mammary gland has been central to the evolution of mammals by being capable of undergoing multiple rounds of substantial remodelling during pregnancy and providing nourishment to the offspring. This plasticity does not ...
Investigating how ubiquitin-mediated proteolysis of AURKA contributes to its activity in the cell cycle Aurora kinase A (AURKA) is a major mitotic regulatory kinase required for mitotic entry, the formation of a bipolar mitotic spindle, and the completion of cytokinesis. In recent years AURKA has been identified as an upstream ...
Arterial thrombosis is the major trigger of myocardial infarction and ischaemic stroke. Although platelets are the most abundant cell in arterial thrombi, platelets interact closely with leukocytes such as monocytes and ...