Department of Haematology
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Maintenance of the marginal-zone B cell compartment specifically requires the RNA-binding protein ZFP36L1 (Nature Publishing Group, 2017-06-01)RNA-binding proteins of the ZFP36 family are best known for inhibiting the expression of cytokines through binding to AU-rich elements in the 3' untranslated region and promoting mRNA decay. Here we identified an indispensable ...
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease (Elsevier, 2017-02-21)BACKGROUND: Genome-wide association studies have so far identified 56 loci associated with risk of coronary artery disease (CAD). Many CAD loci show pleiotropy; that is, they are also associated with other diseases or ...
A log-likelihood-gain intensity target for crystallographic phasing that accounts for experimental error (International Union of Crystallography, 2016-03-01)The crystallographic diffraction experiment measures Bragg intensities; crystallographic electron-density maps and other crystallographic calculations in phasing require structure-factor amplitudes. If data were measured ...