### Recent Submissions

• #### Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. ﻿

(American Society for Clinical Investigation, 2017-01-30)
Platelets are anuclear cells that are essential for blood clotting. They are produced by large polyploid precursor cells called megakaryocytes. Previous genome-wide association studies in nearly 70,000 individuals indicated ...
• #### Rare variants in $\textit{GP1BB}$ are responsible for autosomal dominant macrothrombocytopenia ﻿

(American Society of Hematology, 2017-01-26)
The von Willebrand receptor complex, which is composed of the glycoproteins Ibα, Ibβ, GPV, and GPIX, plays an essential role in the earliest steps in hemostasis. During the last 4 decades, it has become apparent that loss ...