Now showing items 1-20 of 808

• 2'-$\textit{0}$-Methyl-5-hydroxymethylcytidine: A Second Oxidative Derivative of 5-Methylcytidine in RNA ﻿

(American Chemical Society, 2017-02-08)
5-Hydroxymethylcytidine (hm$^{5}$C) was recently identified as a direct metabolite of m$^{5}$C in RNA. We investigated the stability of hm$^{5}$C in human cells using bio-isotopologues and LC-MS/HRMS. This has led to the ...
• 2H and 27Al Solid-State NMR Study of the Local Environments in Aldoped 2-Line Ferrihydrite, Goethite, and Lepidocrocite ﻿

(2015-05-13)
• 5-Formylcytosine alters the structure of the DNA double helix ﻿

(2014-12-15)
• 5-Formylcytosine can be a stable DNA modification in mammals ﻿

(2015-06-22)
• 5-Hydroxymethylcytosine is a predominantly stable DNA modification ﻿

(2014-09-21)
• Ab Initio Atom-Atom Potentials Using CAMCASP: Theory and Application to Many-Body Models for the Pyridine Dimer ﻿

(2016-07-28)
Creating accurate, analytic atom−atom potentials for small organic molecules from first principles can be a time-consuming and computationally intensive task, particularly if we also require them to include explicit ...
• Ab Initio Molecular-Dynamics Simulation of Neuromorphic Computing in Phase-Change Memory Materials ﻿

(2015-06-23)
• Ab initio structure search and in situ 7Li NMR studies of discharge products in the Li-S battery system ﻿

(American Chemical Society, 2014-11-10)

(2009-09)
• Adsorption of atmospheric gases on cementite 010 surfaces. ﻿

(AIP, 2017-05)
We study the adsorption of a series of small molecules on the nonstoichiometric {010} surface of cementite (θ-Fe3C) by means of first-principles calculations. We find that CO, N2, H2O, and CH4 prefer to adsorb over iron ...
• Adsorption of Sodium Hexanoate on α-Alumina ﻿

(2013-06-27)

(2016)
• Advances in Chemical Protein Modification ﻿

(2015-02-20)
• Affinity of IDPs to their targets is modulated by ion-specific changes in kinetics and residual structure ﻿

(National Academy of Sciences, 2017-09-12)
Intrinsically disordered proteins (IDPs) are characterized by a lack of defined structure. Instead, they populate ensembles of rapidly interconverting conformations with marginal structural stabilities. Changes in solution ...
• Aggregation of antibody drug conjugates at room temperature: SAXS and light scattering evidence for colloidal instability of a specific subpopulation ﻿

(2016-04-29)
Coupling a hydrophobic drug onto monoclonal antibodies via lysine residues is a common route to prepare antibody-drug conjugates (ADC), a promising class of biotherapeutics. But a few chemical modifications on protein ...
• Airborne measurements of organic bromine compounds in the Pacific tropical tropopause layer ﻿

(2015-10-26)
• Airport emissions reductions from reduced thrust takeoff operations ﻿

(Elsevier, 2017-05-01)
Given forecast aviation growth, many airports are predicted to reach capacity and require expansion. However, pressure to meet air quality regulations emphasises the importance of efficient ground-level aircraft activities ...
• Allosteric Targeting of Aurora A Kinase Using Small Molecules: A Step Forward Towards Next Generation Medicines? ﻿

(2017-07-27)
• Alpha-2-macroglobulin is acutely sensitive to freezing and lyophilization: Implications for structural and functional studies ﻿

(2015-06-23)
• An alternative derivation of ring-polymer molecular dynamics transition-state theory ﻿

(2016)
In a previous article [T. J. H. Hele and S. C. Althorpe, J. Chem. Phys. 138, 084108 (2013)], we showed that the t → 0+ limit of ring-polymer molecular dynamics (RPMD) rate-theory is also the t → 0+ limit of a new type of ...