Now showing items 1-20 of 595

    • A +1 ribosomal frameshifting motif prevalent among plant amalgaviruses 

      Nibert, Max L.; Pyle, Jesse D.; Firth, Andrew E. (Elsevier, 2016)
      Multiple sequence accessions attributable to novel plant amalgaviruses have been found in the Transcriptome Shotgun Assembly database. Sixteen accessions, derived from 12 different plant species, appear to encompass the ...
    • 2014 European Conference on Donor Health and Management 

      Ramond, Anna; Angelantonio, Emanuele Di (Wiley, 2015-09-01)
      The first European Conference on Donor Health and Management was held in the Hague from 3th- 5th September 2014 and hosted by Sanquin, the Dutch national blood donation organization. This is the first international conference ...
    • 2016 European Guidelines on cardiovascular disease prevention in clinical practice 

      Piepoli, Massimo F.; Hoes, Arno W.; Agewall, Stefan; Albus, Christian; Brotons, Carlos; Catapano, Alberico L.; Cooney, Marie-Therese et al. (Oxford University Press, 2016-05-23)
    • A cluster randomised controlled trial of an occupational therapy intervention for residents with stroke living in UK care homes (OTCH): study protocol 

      Sackley, Cath M.; Burton, Chris R.; Herron-Marx, Sandy; Lett, Karen; Mant, Jonathan; Roalfe, Andrea K.; Sharp, Leslie J. et al. (2012-07-09)
      AbstractBackgroundThe occupational therapy (OT) in care homes study (OTCH) aims to investigate the effect of a targeted course of individual OT (with task training, provision of adaptive equipment, minor environmental ...
    • A qualitative study of participants’ views on re-consent in a longitudinal biobank 

      Dixon-Woods, Mary; Kocman, David; Brewster, Liz; Willars, Janet; Laurie, Graeme; Tarrant, Carolyn (2017-03-23)
      Background Biomedical research increasingly relies on long-term studies involving use and re-use of biological samples and data stored in large repositories or “biobanks” over lengthy periods, often raising questions ...
    • The acceptability of repeat Internet-based hybrid diet assessment of previous 24h dietary intake: Administration of the Oxford WebQ in UK Biobank 

      Galante, Julieta; Adamska, Ligia; Young, Alan; Young, Heather; Littlejohns, Thomas J.; Gallacher, John; Allen, Naomi (Cambridge University Press, 2015-12-11)
      Although dietary intake over a single 24 hour period may be atypical of an individual’s habitual pattern, multiple 24-hour dietary assessments can be representative of habitual intake and help to assess seasonal variation. ...
    • Accuracy of SIAscopy for pigmented skin lesions encountered in primary care: development and validation of a new diagnostic algorithm. 

      Emery, Jon D.; Hunter, Judith; Watson, Antony J.; Hall, Per; Moncrieff, Marc; Walter, Fiona M. (2010-09-25)
      Abstract Background Diagnosing pigmented skin lesions in general practice is challenging. SIAscopy has been shown to increase diagnostic accuracy for melanoma in referred populations. We aimed to develop and validate a ...
    • The adaptation and uptake evaluation of an SMS text message smoking cessation programme (MiQuit) for use in antenatal care 

      Naughton, Felix; Cooper, Sue; Bowker, Katharine; Campbell, Katarzyna; Sutton, Stephen; Leonardi-Bee, Jo; Sloan, Melanie et al. (BMJ Group, 2015-10-22)
      Objectives: To adapt a tailored SMS text message smoking cessation intervention (MiQuit) for use without active health professional endorsement in routine antenatal care settings, to estimate ‘real world’ uptake and test ...
    • Adiposity, hormone replacement therapy use and breast cancer risk by age and hormone receptor status: a large prospective cohort study 

      Ritte, Rebecca; Lukanova, Annekatrin; Berrino, Franco; Dossus, Laure; Tjønneland, Anne; Olsen, Anja; Overvad, Thure F. et al. (2012-05-14)
      Abstract Introduction Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with ...
    • Age- and tumor subtype-specific breast cancer risk estimates for CHEK2*1100delC carriers 

      Schmidt, Marjanka K.; Hogervorst, Frans; van Hien, Richard; Cornelissen, Sten; Broeks, Annegien; Adank, Muriel; Meijers, Hanne et al. (American Society of Clinical Oncology, 2016)
      CHEK2*1100delC is a well-established breast cancer risk variant, most prevalent in European populations. However, there are limited data on risk of breast cancer by age and tumor subtype, limiting its usefulness in breast ...
    • Alcohol consumption and prostate cancer incidence and progression: A Mendelian randomisation study 

      Brunner, Clair; Davies, Neil M.; Martin, Richard M.; Eeles, Rosalind; Easton, Doug; Kote-Jarai, Zsofia; Amin Al Olama, Ali et al. (Wiley, 2016-09-19)
      Prostate cancer is the most common cancer in men in developed countries, and is a target for risk reduction strategies. The effects of alcohol consumption on prostate cancer incidence and survival remain unclear, potentially ...
    • Aligning the planets: The role of nurses in the care of patients with non-ST elevation myocardial infarction 

      Deaton, Christi; Johnson, Rachel; Evans, Maggie; Timmis, Adam; Zaman, Justin; Hemingway, Harry; Hughes, Jacqueline et al. (Wiley, 2016-11-04)
      $\textbf{Background}$ Studies have shown variation in care for patients with non-ST elevation myocardial infarction (NSTEMI), including in the roles of specialist and advanced practice nurses in diagnosis, treatment and ...
    • The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease 

      Astle, William John; Elding, H; Jiang, T; Allen, D; Ruklisa, Dace; Mann, AL; Mead, D et al. (Elsevier, 2016-11-17)
      Many common variants have been associated with hematological traits, but identification of causal genes and pathways has proven challenging. We performed a genome-wide association analysis in the UK Biobank and INTERVAL ...
    • Altering the availability or proximity of food, alcohol and tobacco products to change their selection and consumption 

      Hollands, Gareth John; Carter, Patrice; Shemilt, I; Marteau, Theresa; Jebb, SA; Higgins, J; Ogilvie, D (Wiley-Blackwell, 2017-03-01)
      This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: 1. To assess the impact of altering the availability or proximity of: a) food products (including non-alcoholic beverages); b) alcohol ...
    • An implementation research agenda 

      Eccles, Martin P.; Armstrong, David; Baker, Richard; Cleary, Kevin; Davies, Huw; Davies, Stephen; Glasziou, Paul et al. (2009-04-07)
      Abstract In October 2006, the Chief Medical Officer (CMO) of England asked Professor Sir John Tooke to chair a High Level Group on Clinical Effectiveness in response to the chapter 'Waste not, want not' in the CMOs 2005 ...
    • An investigation of whether factors associated with short-term attrition change or persist over ten years: data from the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) 

      Matthews, Fiona E; Chatfield, Mark; Brayne, Carol; MRC-CFAS (2006-07-18)
      Abstract Background Factors associated with the loss of participants in long-term longitudinal studies of ageing, due to refusal or moves, have been discussed less than those with short term follow-up. Methods In a ...
    • An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation 

      Candido dos Reis, Francisco J; Wishart, Gordon C; Dicks, Ed M; Greenberg, David; Rashbass, Jem; Schmidt, Marjanka K; van den Broek, Alexandra J et al. (2017-05-22)
      Abstract Background PREDICT is a breast cancer prognostic and treatment benefit model implemented online. The overall fit of the model has been good in multiple independent ...
    • Annexin A1 expression in breast cancer: tumor subtypes and prognosis 

      Sobral-Leite, Marcelo; Wesseling, Jelle; Smit, Vincent T. H. B. M.; Nevanlinna, Heli; van Miltenburg, Martine H.; Sanders, Joyce; Hofland, Ingrid et al. (BioMed Central, 2015-06-25)
      Background Annexin A1 (ANXA1) is a protein related with the carcinogenesis process and metastasis formation in many tumors. However, little is known about the prognostic value of ANXA1 in breast cancer. The purpose of ...
    • Antenatal Clinic and Stop Smoking Services Staff Views on “Opt-Out” Referrals for Smoking Cessation in Pregnancy: A Framework Analysis 

      Campbell, Katarzyna Anna; Bowker, Katharine Anna; Naughton, Felix; Sloan, Melanie; Cooper, Sue; Coleman, Tim (Molecular Diversity Preservation International, 2016-10-12)
      $\textbf{Introduction}$: UK guidance recommends routine exhaled carbon monoxide (CO) screening for pregnant women and “opt-out” referrals to stop smoking services (SSS) of those with CO ≥ 4 ppm. We explored staff views on ...