Trends in modeling Biomedical Complex Systems.
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Authors
Milanesi, Luciano
Romano, Paolo
Castellani, Gastone
Remondini, Daniel
Liò, Petro
Abstract
In this paper we provide an introduction to the techniques for multi-scale complex biological systems, from the single bio-molecule to the cell, combining theoretical modeling, experiments, informatics tools and technologies suitable for biological and biomedical research, which are becoming increasingly multidisciplinary, multidimensional and information-driven. The most important concepts on mathematical modeling methodologies and statistical inference, bioinformatics and standards tools to investigate complex biomedical systems are discussed and the prominent literature useful to both the practitioner and the theoretician are presented.
Description
Keywords
Computational Biology, Disease, Humans, Models, Biological, Systems Biology
Journal Title
BMC Bioinformatics
Conference Name
Journal ISSN
1471-2105
1471-2105
1471-2105
Volume Title
Publisher
Springer Science and Business Media LLC