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Trends in modeling Biomedical Complex Systems.


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Authors

Milanesi, Luciano 
Romano, Paolo 
Castellani, Gastone 
Remondini, Daniel 
Liò, Petro 

Abstract

In this paper we provide an introduction to the techniques for multi-scale complex biological systems, from the single bio-molecule to the cell, combining theoretical modeling, experiments, informatics tools and technologies suitable for biological and biomedical research, which are becoming increasingly multidisciplinary, multidimensional and information-driven. The most important concepts on mathematical modeling methodologies and statistical inference, bioinformatics and standards tools to investigate complex biomedical systems are discussed and the prominent literature useful to both the practitioner and the theoretician are presented.

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Keywords

Computational Biology, Disease, Humans, Models, Biological, Systems Biology

Journal Title

BMC Bioinformatics

Conference Name

Journal ISSN

1471-2105
1471-2105

Volume Title

Publisher

Springer Science and Business Media LLC