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dc.contributor.authorTelalagic, Selmaen_GB
dc.date.accessioned2012-11-15T15:25:52Z
dc.date.available2012-11-15T15:25:52Z
dc.date.issued2012-05-30en_GB
dc.identifier.otherCWPE1229
dc.identifier.urihttp://www.dspace.cam.ac.uk/handle/1810/243962
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/243962
dc.description.abstractThis paper explores optimal treatment of an SIS (Susceptible-Infected-Susceptible) disease that has two strains with diᄂerent infectivities. When we assume that neither eradication nor full infection are possible, it is shown that there are two categories of equilibria. First, there are two continua of interior equilibria characterised by a fixed, positive total level of infection, where both strands of the disease prevail. It is hypothesised that a Skiba curve of indiᄂerence lies between them. Second, there are two sets of equilibria where one strand of the disease is eradicated asymptotically. The feasibility of equilibria depends on parameter assumptions; a combination of low natural rate of recovery and large diᄂerence between infectivities leaves only a small proportion of equilibria as feasible. Simulations exploring the relationship between cost and optimal policy are carried out. There exists a parameter range such that, counter-intuitively, it is optimal to allow the high-infectivity strain of the disease to prevail, while asymptotically eradicating the low-infectivity strain. Within this parameter range, there is added benefit from policy flexibility. At higher costs, simulations of the interior equilibria demonstrate the existence of a Skiba curve. The curve delineates two regions, each of which has a clear optimal policy.en_GB
dc.publisherFaculty of Economics
dc.relation.ispartofseriesCambridge Working Papers in Economics
dc.rightsAll Rights Reserveden
dc.rights.urihttps://www.rioxx.net/licenses/all-rights-reserved/en
dc.subjectEpidemiological modellingen_GB
dc.subjectOptimal controlen_GB
dc.subjectSimulationsen_GB
dc.titleOptimal Treatment of an SIS Disease with Two Strainsen_GB
dc.typeWorking Paperen_GB
dc.identifier.doi10.17863/CAM.5233
dc.identifier.urlhttp://www.econ.cam.ac.uk/dae/repec/cam/pdf/cwpe1229.pdf


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