Research Data - Cancer Research UK Cambridge Institute

Research data supporting “MRI measurements of reporter-mediated increases in transmembrane water exchange enable detection of a gene reporter”

Schilling, Franz; Ros, Susana; Hu, De-En; D'Santos, Paula; McGuire, Sarah; Mair, Richard; Wright, AlanMannion, ElizabethFranklin, Robin J. M.Neves, André A.Brindle, Kevin M. et al.
Methanol-based fixation is superior to buffered formalin for next-generation sequencing of DNA from clinical cancer samples

Piskorz, A. M.; Ennis, D.; Macintyre, G.; Goranova, T. E.; Eldridge, M.; Segui-Gracia, N.; Valganon, M.Hoyle, A.Orange, C.Moore, L.Jimenez-Linan, M.Millan, D.McNeish, I. A.Brenton, J. D. et al. (Oxford University Press, 2015-12-17)

Background Next-generation sequencing (NGS) of tumour samples is a critical component of personalised cancer treatment, but it requires high-quality DNA samples. Routine neutral-buffered formalin (NBF) fixation has ...