Seasonal variation in diagnosis of invasive cutaneous melanoma in Eastern England and Scotland
Brewster, David H
Corrie, Pippa G
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Walter, F., Abel, G., Lyratzopoulos, G., Melia, J., Greenberg, D., Brewster, D. H., Butler, H., et al. (2015). Seasonal variation in diagnosis of invasive cutaneous melanoma in Eastern England and Scotland. Cancer Epidemiology, 39 554-561. https://doi.org/10.1016/j.canep.2015.06.006
Background Worldwide, the incidence of cutaneous melanoma has been reported to be highest in the summer and lowest in the winter. Northern Irish data suggested seasonal variation for women only, especially those with thinner melanomas, sited on limbs. We interrogated two larger UK cancer registries for temporal differences in melanoma diagnosis and associated patient characteristics. Methods Melanomas diagnosed from 2006 to 2010 in the Eastern England and Scottish cancer registries (n=11,611) were analysed by month of diagnosis, patient demographics and melanoma characteristics, using descriptive and multivariate modelling methods. Results More patients with melanoma were diagnosed in the summer months (June 9.9%, July 9.7%, August 9.8%) than the winter months (December 7.2%, January 7.2%, February 7.1%) and this pattern was consistent in both regions. There was evidence that the seasonal patterns varied by sex (p=0.015), melanoma thickness (p=0.002), body site (p=0.006), and type (superficial spreading melanomas p=0.005). The seasonal variation was greatest for diagnosis of melanomas occurring on the limbs. Conclusion This study has confirmed seasonal variation in melanoma diagnosis in Eastern England and Scotland across almost all population demographics and melanoma characteristics studied, with higher numbers diagnosed in the summer months, particularly on the limbs. Seasonal patterns in skin awareness and related help-seeking are likely to be implicated. Targeted patient interventions to increase sun awareness and encourage year-long skin inspection are warranted.
The paper was materially supported by the National Institute for Health Research (NIHR-CS-012-030), supporting FMW through a Clinician Scientist award. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health. During this project, GL was supported by a post-doctoral fellowship by the National Institute for Health Research (PDF-2011-04-047) to the end of 2014; and by a Cancer Research UK Clinician Scientist Fellowship award (A18180) from March 2015.
National Institute for Health Research (NIHR-CS-012-030)
External DOI: https://doi.org/10.1016/j.canep.2015.06.006
This record's URL: https://www.repository.cam.ac.uk/handle/1810/248739
Licence URL: http://creativecommons.org/licenses/by/4.0/
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