Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome

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Authors

  Day, Felix

Hinds, David A

Tung, Joyce Y

Stock, Lisette

Styrkarsdottir, Unnur

Saxena, Richa

Bjonnes, Andrew

Broer, Linda

  Dunger, David

Halldorsson, Bjarni V

Lawlor, Debbie A

Laval, Guillame

Mathieson, Iain

McCardle, Wendy L

Louwers, Yvonne

Meun, Cindy

Ring, Susan

Scott, Robert

Sulem, Patrick

Uitterlinden, André G

  Wareham, Nicholas

Thorsteinsdottir, Unnur

Welt, Corrine

Stefansson, Kari

Laven, Joop SE

  Ong, Kenneth

  Perry, John

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Publication Date

2015-09-29

Journal Title

Nature Communications

ISSN

2041-1723

Publisher

Nature Publishing Group

Volume

6

Number

8464

Language

English

Type

Article

Metadata

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Citation

Day, F., Hinds, D. A., Tung, J. Y., Stock, L., Styrkarsdottir, U., Saxena, R., Bjonnes, A., et al. (2015). Causal mechanisms and balancing selection inferred from genetic associations with polycystic ovary syndrome. Nature Communications, 6 (8464) https://doi.org/10.1038/ncomms9464

Sponsorship

This work was supported by the Medical Research Council [U106179472; MC_U106179472; U106179471; MC_U106179471] and the National Human Genome Research Institute of the National Institutes of Health (grant number R44HG006981 to 23andMe). The UK Medical Research Council and Wellcome Trust (092731), together with the University of Bristol, provide core support for the ALSPAC study. AMH assays in ALSPAC were funded with a grant from the US National Institute of Health (R01 DK077659). DAL works in a unit that receives funding from the University of Bristol and the UK Medical Research Council (MC_UU_12013/5).

Funder references

MRC (MC_UU_12015/2)

MRC (MC_UU_12015/1)

MRC (G0600717)

Medical Research Council (MC_U106179471)

Identifiers

External DOI: https://doi.org/10.1038/ncomms9464

This record's URL: https://www.repository.cam.ac.uk/handle/1810/249191



Rights

Attribution 2.0 UK: England & Wales

Licence URL: http://creativecommons.org/licenses/by/2.0/uk/