FlyBase: establishing a Gene Group resource for Drosophila melanogaster
Attrill, Helen Louise
Goodman, Joshua L
Rey, Alix J
Nucleic Acids Research
Oxford University Press
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Attrill, H. L., Falls, K., Goodman, J. L., Millburn, G., Antonazzo, G., Rey, A. J., Marygold, S., & et al. (2015). FlyBase: establishing a Gene Group resource for Drosophila melanogaster. Nucleic Acids Research, 44 D786-D792. https://doi.org/10.1093/nar/gkv1046
Many publications describe sets of genes or gene products that share a common biology. For example, genome-wide studies and phylogenetic analyses identify genes related in sequence; high-throughput genetic and molecular screens reveal functionally related gene products; and advanced proteomic methods can determine the subunit composition of multi-protein complexes. It is useful for such gene collections to be presented as discrete lists within the appropriate Model Organism Database (MOD) so that researchers can readily access these data alongside other relevant information. To this end, FlyBase (flybase.org), the MOD for Drosophila melanogaster, has established a ‘Gene Group’ resource: highquality sets of genes derived from the published literature and organized into individual report pages. To facilitate further analyses, Gene Group Reports also include convenient download and analysis options, together with links to equivalent gene groups at other databases. This new resource will enable researchers with diverse backgrounds and interests to easily view and analyse acknowledged D. melanogaster gene sets and compare them with those of other species.
Drosophila, Gene families, Protein Complexes, Paralogs
This work was supported by the National Human Genome Research Institute at the National Institutes of Health [U41 HG000739 to W.G.] and the Medical Research Council (UK) [G1000968 to N.B.]. Funding for open access charges: National Human Genome Research Institute at the National Institutes of Health [U41 HG000739 to W.G.].
National Human Genome Research Institute (NHGRI) (P41HG000739)
External DOI: https://doi.org/10.1093/nar/gkv1046
This record's URL: https://www.repository.cam.ac.uk/handle/1810/251282
Creative Commons Attribution 4.0
Licence URL: http://creativecommons.org/licenses/by/4.0/