Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes.
Journal of Diabetes Science and Technology
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Tauschmann, M., Thabit, H., Leelarathna, L., Elleri, D., Allen, J., Lubina-Solomon, A., Stadler, M., et al. (2015). Factors Associated With Glycemic Control During Free-Living Overnight Closed-Loop Insulin Delivery in Children and Adults With Type 1 Diabetes.. Journal of Diabetes Science and Technology, 9 (6), 1346-1347. https://doi.org/10.1177/1932296815604439
Unsupervised free-living overnight home use of closed-loop insulin delivery is feasible, safe, and effective in adolescents1 and adults2 with type 1 diabetes, but outcomes vary between individuals. Understanding factors influencing glucose outcomes may help to identify vulnerable populations, guide design of future studies, and lead to enhanced control algorithms.
closed-loop insulin delivery, glycemic control, home study, predictive factors, type 1 diabetes, Adolescent, Adult, Age Factors, Biomarkers, Blood Glucose, Diabetes Mellitus, Type 1, Hemoglobin A, Glycosylated, Humans, Hypoglycemia, Hypoglycemic Agents, Insulin, Insulin Infusion Systems, Linear Models, Randomized Controlled Trials as Topic, Risk Factors, Time Factors, Treatment Outcome
Funding for these studies was received from the JDRF (#22-2009-802) and Diabetes UK (BDA07/0003549), with additional support for the Artificial Pancreas work by National Institute of Diabetes and Digestive and Kidney Diseases (1R01DK085621), Wellcome Strategic Award (100574/Z/12/Z), and National Institute for Health Research Cambridge Biomedical Research Centre.
Cambridge University Hospitals NHS Foundation Trust (CUH) (Roman Hovorka)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (R01DK085621)
Wellcome Trust (100574/Z/12/Z)
External DOI: https://doi.org/10.1177/1932296815604439
This record's URL: https://www.repository.cam.ac.uk/handle/1810/252353
Creative Commons Attribution 4.0 International License
Licence URL: http://creativecommons.org/licenses/by/4.0/