Comparison of 2 chromogenic media for the detection of extended-spectrum β-lactamase producing Enterobacteriaceae stool carriage in nursing home residents.
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Authors
Abstract
ChromID ESBL agar and Brilliance ESBL agar were compared for the isolation of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae from 298 stools. These had comparable sensitivity and selectivity for the 116 positive samples. Pre-enrichment with cefpodoxime and extending incubation to 48 hours after direct plating both significantly increased sensitivity but reduced selectivity of both agars.
Description
Keywords
Chromogenic agar, Detection, Enterobacteriaceae, Extended-spectrum β-lactamase, Selectivity, Sensitivity, Anti-Bacterial Agents, Carrier State, Ceftizoxime, Disk Diffusion Antimicrobial Tests, Enterobacteriaceae, Enterobacteriaceae Infections, Feces, Humans, Nursing Homes, Sensitivity and Specificity, beta-Lactamases, Cefpodoxime
Journal Title
Diagn Microbiol Infect Dis
Conference Name
Journal ISSN
0732-8893
1879-0070
1879-0070
Volume Title
84
Publisher
Elsevier BV
Publisher DOI
Sponsorship
Academy of Medical Sciences (unknown)
Medical Research Council (MR/N029399/1)
Wellcome Trust (098600/Z/12/Z)
Medical Research Council (MR/N029399/1)
Wellcome Trust (098600/Z/12/Z)
This work was supported by a grant awarded to SP from the UK Department of Health, Wellcome Trust and the Health Innovation Challenge Fund (HICF-T5-342 and WT098600). TG is a Wellcome Trust Research Training Fellow. MET is a Clinician Scientist Fellow, supported by the Academy of Medical Sciences and the Health Foundation. The authors declare no conflicts of interest.