Research data supporting "A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters"
Repository URI
Repository DOI
Loading...
Type
Dataset
Change log
Authors
Nikiforov, Petar O.
Surade, Sachin
Blaszczyk, Michal
Blundell, Tom L.
Abell, Chris
Description
Characterisation of compounds described in the paper - 1H and 13C NMR spectra, High resolution mass spectra, LCMS spectra, IR spectra. Isothermal titration calorimetry (ITC) and surface plasmon resonance (SPR) data associated with the publication is also included.
This record supports publication titled "A fragment merging approach towards the development of small molecule inhibitors of Mycobacterium tuberculosis EthR for use as ethionamide boosters" published in Organic & Biomolecular Chemistry (http://dx.doi.org/10.1039/C5OB02630J)
Version
Software / Usage instructions
.pdf .zip
Keywords
EthR, inhibitors, tuberclosis, ethionamide, boosters
Publisher
University of Cambridge
Sponsorship
This work was supported by the EPSRC, Bill and Melinda Gates Foundation, the EU FP7 [grant number MM4TB Grant number 260872], the ERC-STG INTRACELLTB [grant number 260901], the Agence Nationale de la Recherche [grant number ANR-10-EQPX-04-01], the Feder [grant number 12001407 (D-AL) Equipex Imaginex BioMed] and the Région Nord Pas de Calais, France.