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dc.contributor.authorTesoro, Salvatoreen
dc.contributor.authorAhnert, Sebastianen
dc.date.accessioned2016-03-22T11:38:41Z
dc.date.available2016-03-22T11:38:41Z
dc.date.issued2016en
dc.identifier.citationTesoro & Ahnert. Physical Review E (2016)en
dc.identifier.issn2470-0045
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/254611
dc.description.abstractSelf-assembly is ubiquitous in nature, particularly in biology, where it underlies the formation of protein quaternary structure and protein aggregation. Quaternary structure assembles deterministically and performs a wide range of important functions in the cell, whereas protein aggregation is the hallmark of a number of diseases and represents a non-deterministic self-assembly process. Here we build on previous work on a lattice model of deterministic self-assembly to investigate non-deterministic self-assembly of single lattice tiles and mixtures of two tiles at varying relative concentrations. Despite limiting the simplicity of the model to two interface types, which results in 13 topologically distinct single tiles and 106 topologically distinct sets of two tiles, we observe a wide variety of concentration-dependent behaviours. Several two-tile sets display critical behaviours in form of a sharp transition from bound to unbound structures as the relative concentration of one tile to another increases. Other sets exhibit gradual monotonic changes in structural density, or non-monotonic changes, while again others show no concentration dependence at all. We catalogue this extensive range of behaviours and present a model that provides a reasonably good estimate of the critical concentrations for a subset of the critical transitions. In addition we show that the structures resulting from these tile sets are fractal, with one of two different fractal dimensions
dc.languageEnglishen
dc.language.isoenen
dc.publisherAmerican Physical Society
dc.rightsAttribution-NonCommercial 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/
dc.titleNon-deterministic self-assembly of two tile types on a latticeen
dc.typeArticle
dc.description.versionThis is the author accepted manuscript. It is currently under an indefinite embargo pending publication by the American Physical Society.en
prism.publicationDate2016en
prism.publicationNamePhysical Review Een
dc.rioxxterms.funderEPSRC
datacite.cites.urlhttps://www.repository.cam.ac.uk/handle/1810/254546
dcterms.dateAccepted2016-03-08en
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2016en
dc.contributor.orcidTesoro, Salvatore [0000-0003-4011-366X]
dc.identifier.eissn2470-0053
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idEPSRC (EP/L504920/1)


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Attribution-NonCommercial 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial 4.0 International