Fat eggs shape offspring health.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Watson, Erica D
Rakoczy, Joanna
Abstract
How maternal diet influences offspring metabolism is unclear, as it is difficult to distinguish between the effects of the in utero environment and epigenetic factors contributed by the oocyte. In a mouse model of high-fat diet, a new study teases apart these mechanisms by using in vitro fertilization and shows that susceptibility of offspring to metabolic disorder can likely be attributed to epigenetic inheritance via the oocyte.
Description
Keywords
Animals, Diet, High-Fat, Humans
Journal Title
Nat Genet
Conference Name
Journal ISSN
1061-4036
1546-1718
1546-1718
Volume Title
Publisher
Springer Science and Business Media LLC