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Emergent patterns from probabilistic generalizations of lateral activation and inhibition.

Published version
Peer-reviewed

Repository DOI


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Authors

Kabla, Alexandre 

Abstract

The combination of laterally activating and inhibiting feedbacks is well known to spontaneously generate spatial organization. It was introduced by Gierer and Meinhardt as an extension of Turing's great insight that two reacting and diffusing chemicals can spontaneously drive spatial morphogenesis per se In this study, we develop an accessible nonlinear and discrete probabilistic model to study simple generalizations of lateral activation and inhibition. By doing so, we identify a range of modes of morphogenesis beyond the familiar Turing-type modes; notably, beyond stripes, hexagonal nets, pores and labyrinths, we identify labyrinthine highways, Kagome lattices, gyrating labyrinths and multi-colour travelling waves and spirals. The results are discussed within the context of Turing's original motivating interest: the mechanisms which underpin the morphogenesis of living organisms.

Description

Keywords

lateral inhibition, nonlinear stochastic model, pattern formation, Models, Theoretical

Journal Title

J R Soc Interface

Conference Name

Journal ISSN

1742-5689
1742-5662

Volume Title

13

Publisher

The Royal Society
Sponsorship
This work began while L.W. was supported by an EPSRC fellowship.