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dc.contributor.authorUsher-Smith, Juliet A
dc.contributor.authorSharp, Stephen J
dc.contributor.authorGriffin, Simon J
dc.date.accessioned2016-05-10T10:56:18Z
dc.date.available2016-05-10T10:56:18Z
dc.date.issued2016-06-22
dc.identifier.issn0959-8146
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/255949
dc.description.abstractThe spectrum effect describes the variation between settings in performance of tests used to predict, screen for, and diagnose disease. In particular, the predictive use of a test may be different when it is applied in a general population rather than in the study sample in which it was first developed. This article discusses the impact of the spectrum effect on measures of test performance, and its implications for the development, evaluation, application, and implementation of such tests.
dc.description.sponsorshipJUS is supported by a National Institute of Health Research (NIHR) Clinical Lectureship. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. SJS is supported by the Medical Research Council www.mrc.ac.uk [Unit Programme number MC_UU_12015/1].
dc.languageEnglish
dc.language.isoen
dc.publisherBMJ
dc.rightsAttribution 4.0 International
dc.rightsAttribution 4.0 International
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.titleThe spectrum effect in tests for risk prediction, screening, and diagnosis.
dc.typeArticle
dc.description.versionThis is the final version of the article. It first appeared from the BMJ Group via https://doi.org/10.1136/bmj.i3139
prism.numberi3139
prism.publicationDate2016
prism.publicationNameBMJ
prism.volume353
dc.rioxxterms.funderNIHR
dc.rioxxterms.funderMRC
dc.rioxxterms.projectidMC_UU_12015/1
dcterms.dateAccepted2016-04-28
rioxxterms.versionofrecord10.1136/bmj.i3139
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
rioxxterms.licenseref.startdate2016-06-22
dc.contributor.orcidUsher-Smith, Juliet [0000-0002-8501-2531]
dc.contributor.orcidSharp, Stephen [0000-0003-2375-1440]
dc.contributor.orcidGriffin, Simon [0000-0002-2157-4797]
dc.identifier.eissn1756-1833
rioxxterms.typeJournal Article/Review
pubs.funder-project-idMedical Research Council (MC_UU_12015/4)
pubs.funder-project-idMedical Research Council (MC_UU_12015/1)
pubs.funder-project-idMedical Research Council (MC_U106179474)
cam.issuedOnline2016-06-22
cam.orpheus.successThu Jan 30 12:54:19 GMT 2020 - The item has an open VoR version.
rioxxterms.freetoread.startdate2100-01-01


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International