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Clinical Studies Using Biological and Synthetic Materials for Meniscus Replacement.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Lin, David D 
Picardo, Natasha E 
Adesida, Adetola 
Khan, Wasim S 

Abstract

Meniscal injury is a common problem among sportsmen and increasingly seen in the older and more active population. The traditional treatment options include a partial meniscectomy, which provides good mechanical and pain relief to the patient. However, the focus of treatment is shifting towards repairing meniscal tears where possible and replacement of the lost meniscal tissue where appropriate. Replacement can be total or partial. Total meniscal replacement using an allograft, is usually reserved for young patients, who meet certain criteria and who have undergone several subtotal meniscectomies or a single stage total meniscectomy and are still symptomatic. Partial meniscal replacement can be utilized in conjunction with a partial meniscectomy to fill the resulting space left by the resection. Collagen based implants and synthetic scaffolds have entered the European market but have demonstrated mixed results in clinical trials. Tissue engineering to create an implant that mimics the biomechanical properties holds much potential for future research.

Description

Keywords

Meniscal replacement, biological material, meniscal injury, meniscal substitute, meniscectomy, tissue engineering, Allografts, Arthroplasty, Replacement, Biocompatible Materials, Clinical Trials as Topic, Humans, Joint Prosthesis, Knee Injuries, Menisci, Tibial, Tibial Meniscus Injuries

Journal Title

Curr Stem Cell Res Ther

Conference Name

Journal ISSN

1574-888X
2212-3946

Volume Title

11

Publisher

Bentham Science Publishers Ltd.