The Emerging Role of MRI in Prostate Cancer Active Surveillance and Ongoing Challenges.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Barrett, Tristan https://orcid.org/0000-0002-1180-1474
Haider, Masoom A
Abstract
OBJECTIVE: Active surveillance (AS) has emerged as a management strategy for preventing overtreatment of indolent prostate cancer. Selection of patients for AS has traditionally proved challenging and resulted in 20-30% misclassification rates. MRI has potential to help overcome this limitation, broaden selection criteria to increase recruitment, and minimize the invasive nature of AS follow-up. CONCLUSION: The main issues surrounding MRI and AS are the heterogeneity of inclusion criteria, the definition of significant disease, and agreement about what constitutes radiologic progression. Prospective cohorts with MRI at enrollment and long-term follow-up are required to further address these issues.
Description
Keywords
active surveillance, multiparametric MRI, prostate cancer, Evidence-Based Medicine, Forecasting, Humans, Image Enhancement, Magnetic Resonance Imaging, Male, Neoplasm Staging, Prostatic Neoplasms, Reproducibility of Results, Sensitivity and Specificity, Watchful Waiting
Journal Title
AJR. American journal of roentgenology
Conference Name
Journal ISSN
0361-803X
1546-3141
1546-3141
Volume Title
208
Publisher
American Roentgen Ray Society