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Independence of epigenetic and genetic diversity in AML.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Sasca, Daniel 
Huntly, Brian JP 

Abstract

A new study provides the first insights into epigenetic heterogeneity in AML. The study highlights a striking independence of genetic and epigenetic variation, and links the kinetics of epigenetic change to clinical outcome.

Description

Keywords

Epigenesis, Genetic, Epigenomics, Genetic Variation, Humans, Leukemia, Myeloid, Acute

Journal Title

Nat Med

Conference Name

Journal ISSN

1078-8956
1546-170X

Volume Title

22

Publisher

Springer Science and Business Media LLC
Sponsorship
Medical Research Council (MR/M010392/1)
Medical Research Council (MC_PC_12009)
Worldwide Cancer Research (None)
Medical Research Council, Wellcome Trust, Mildred-Scheel Organisation