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dc.contributor.authorHaapala, Eero Aen
dc.contributor.authorVäistö, Juusoen
dc.contributor.authorVeijalainen, Aapoen
dc.contributor.authorLintu, Niinaen
dc.contributor.authorWiklund, Petrien
dc.contributor.authorWestgate, Kateen
dc.contributor.authorEkelund, Ulfen
dc.contributor.authorLindi, Virpien
dc.contributor.authorBrage, Sorenen
dc.contributor.authorLakka, Timo Aen
dc.date.accessioned2017-01-17T10:11:14Z
dc.date.available2017-01-17T10:11:14Z
dc.date.issued2017-08en
dc.identifier.issn0899-8493
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/261895
dc.description.abstract$\textbf{Purpose:}$ To investigate the relationships of objectively measured physical activity (PA) and sedentary time (ST) to arterial stiffness in pre-pubertal children. $\textbf{Method:}$ Altogether 136 children (57 boys, 79 girls) aged 6–8-years participated in the study. Stiffness index (SI) was assessed by pulse contour analysis based on photoplethysmography. ST, light PA, moderate PA, and vigorous PA were assessed using combined acceleration and heart rate monitoring. We investigated the associations of ST (<1.5METs) and time spent in intensity level of PA above 2–7METs in min/d with SI using linear regression analysis. We studied the optimal duration and intensity of PA to identify children being in the highest quarter of SI using Receiver Operating Characteristics curves. $\textbf{Results:}$ Moderate PA, vigorous PA, and cumulative time spent in PA above 3 ($\beta$=–0.279, $P$=0.002), 4 ($\beta$=–0.341, $P$<0.001), 5 ($\beta$=–0.349, $P$<0.001), 6 ($\beta$=–0.312, $P$<0.001), and 7 ($\beta$=–0.254, $P$=0.005) METs were inversely associated with SI after adjustment for age, sex, and monitor wear time. The cutoffs for identifying children being in the highest quarter of SI <68 min/d for PA exceeding 5 METs and <26 min/d for PA exceeding 6 METs. $\textbf{Conclusion:}$ Lower levels of PA exceeding 3–6 METs were related to higher arterial stiffness in children.
dc.description.sponsorshipThe PANIC Study is funded by Jenny and Antti Wihuri Foundation, Päivikki and Sakari Sohlberg Foundation, Ministry of Social Affairs and Health of Finland, Ministry of Education and Culture of Finland, University of Eastern Finland, Finnish Innovation Fund Sitra, Social Insurance Institution of Finland, Finnish Cultural Foundation, Juho Vainio Foundation, Foundation for Paediatric Research, Paavo Nurmi Foundation, Paulo Foundation, Diabetes Research Foundation, Research Committee of the Kuopio University Hospital Catchment Area (State Research Funding) and Kuopio University Hospital (EVO funding number 5031343), City of Kuopio. The work of KW, UE, and SB is supported by the UK Medical Research Council (MC_UU_12015/3).
dc.format.mediumPrint-Electronicen
dc.languageengen
dc.publisherHuman Kinetics Publishers, Inc.
dc.titleAssociations of Objectively Measured Physical Activity and Sedentary Time With Arterial Stiffness in Pre-Pubertal Children.en
dc.typeArticle
prism.endingPage335
prism.publicationDate2017en
prism.publicationNamePediatric exercise scienceen
prism.startingPage326
prism.volume29en
dc.identifier.doi10.17863/CAM.7129
dcterms.dateAccepted2016-12-21en
rioxxterms.versionofrecord10.1123/pes.2016-0168en
rioxxterms.versionAMen
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2017-08en
dc.contributor.orcidWestgate, Kate [0000-0002-0283-3562]
dc.contributor.orcidBrage, Soren [0000-0002-1265-7355]
dc.identifier.eissn1543-2920
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idMRC (MC_UU_12015/3)


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