Single-molecule force spectroscopy quantification of adhesive forces in cucurbit[8]uril host-guest ternary complexes.
Authors
Walsh-Korb, Z
Yu, Y
Janecek, E-R
Del Barrio, J
Williams, PE
Zhang, X
Publication Date
2017-01-05Journal Title
Langmuir
ISSN
0743-7463
Publisher
ACS Publications
Volume
33
Issue
6
Pages
1343-1350
Language
eng
Type
Article
This Version
AM
Metadata
Show full item recordCitation
Walsh-Korb, Z., Yu, Y., Janecek, E., Lan, Y., Del Barrio, J., Williams, P., Zhang, X., & et al. (2017). Single-molecule force spectroscopy quantification of adhesive forces in cucurbit[8]uril host-guest ternary complexes.. Langmuir, 33 (6), 1343-1350. https://doi.org/10.1021/acs.langmuir.6b03457
Abstract
Cucurbit[8]uril (CB[8]) heteroternary complexes display certain characteristics making them well-suited for molecular level adhesives. In particular, the ability to control adhesion through careful choice of host-guest binding pairs enables specific, fully reversible adhesion. Understanding the effect of the environment on the adhesive system is also critical when developing new molecular level adhesives. Here we explore the binding forces involved in the methyl viologen · CB[8] · napthol heteroternary complex using single-molecule force spectroscopy (SMFS) under a variety of conditions. From SMFS, the interaction of a single ternary complex was found to be in the region of 140 pN. Additionally, a number of surface interactions could be readily differentiated using the SMFS technique allowing for a deeper understanding of the dynamic heteroternary CB[8] system on the single-molecule scale.
Sponsorship
This work was supported in part by the Engineering and Physical Sciences Research Council (EPSRC), the Walters-Kundert Charitable Trust and an ERC Starting Investigator grant (ASPiRe, 240629). ZWK, ERJ, YL thank the Royal Society of Chemistry for a grant allowing travel to Tsinghua University to carry out this research. YY would like to acknowledge financial support from the Young Scientists of the National Science Foundation of China (21304052). YL thanks the Chinese Overseas Scholarship Trust for financial support. JdB thanks the Marie Curie Actions program for financial support. PEW thanks the Atomic Weapons and Energy Commission and the Melville Laboratory for Polymer Synthesis for financial support.
Funder references
European Research Council (240629)
European Commission (273807)
Royal Society (IE130941)
EPSRC (EP/K039520/1)
Identifiers
External DOI: https://doi.org/10.1021/acs.langmuir.6b03457
This record's URL: https://www.repository.cam.ac.uk/handle/1810/261960
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