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Research data supporting "A Novel Methodology for the Incorporation of Chiral Linkers in Stapled Peptides"


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Type

Dataset

Change log

Authors

Sipthorp, James 
Xu, Wenshu 
Itzhaki, Laura 
Ley, Steven V. 

Description

This file contains organic compound characterisation data and peptide characterisation data for the project "A Novel Methodology for the Incorporation of Chiral Linkers in Stapled Peptides" Organic Data: ChemDraw Structure, NMR, IR, HRMS, and HPLC data (if applicable) of compounds 1-9 Peptide Data: HPLC purity, HRMS, Circular Dichroism, proteolytic assay, and fluorescence polarisation assay data for all purified peptides.

Version

Software / Usage instructions

ChemDraw OpenChrom (for .D HPLC files; other programs applicable) AdobeReader MestReNova Microsoft Excel

Keywords

stapled peptide, two-component stapling, protein-protein interactions, solid-phase synthesis

Publisher

University of Cambridge
Sponsorship
EPSRC [EP/K009494/1, EP/M004120/1 and EP/K/039520/1], Gates-Cambridge Trust
Relationships
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