Cobalt-catalysed C–H carbonylative cyclisation of aliphatic amides
Published version
Peer-reviewed
Repository URI
Repository DOI
Type
Article
Change log
Authors
Williamson, P
Galván, A
Gaunt, MJ
Abstract
A cobalt-catalysed C–H carbonylation of aliphatic carboxamide derivatives is described, employing commercially available Co(II)-salts in the presence of a silver oxidant. This operationally simple process utilises an atmospheric pressure of CO and generates a range of substituted succinimide products bearing diverse functional groups that can be successfully accessed via this methodology.
Description
Keywords
0399 Other Chemical Sciences
Journal Title
Chemical Science
Conference Name
Journal ISSN
2041-6520
2041-6539
2041-6539
Volume Title
Publisher
Royal Society of Chemistry
Publisher DOI
Sponsorship
The Royal Society (wm140104)
European Research Council (259711)
Engineering and Physical Sciences Research Council (EP/I00548X/1)
European Research Council (259711)
Engineering and Physical Sciences Research Council (EP/I00548X/1)
We are grateful to the Herchel Smith Foundation for a scholarship (P. W.) and the Royal Society (Wolfson Merit Award, M. J. G) and the EPSRC (EP/100548X/1) and ERC (ERC-StG-259711) for Fellowships (M. J. G). Mass spectrometry data were acquired at the EPSRC UK National Mass Spectrometry Facility at Swansea University.