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dc.contributor.authorWhitmarsh, Tristanen
dc.contributor.authorTreece, Grahamen
dc.contributor.authorGee, Andrewen
dc.contributor.authorPoole, Kennethen
dc.date.accessioned2017-04-28T15:39:18Z
dc.date.available2017-04-28T15:39:18Z
dc.date.issued2017-02-23en
dc.identifier.issn1861-6410
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/263894
dc.description.abstractPurpose The aim of this study was to develop and evaluate a method for measuring the cortical bone thickness from computed tomography (CT) scans with metallic implants and to assess the benefits of metal artefact removal software. Methods A previously validated technique based on the fitting of a cortical model was modified to also model metal structures when required. Cortical thickness measurements were taken over intact bone segments and compared with the corresponding contralateral bone segment. The evaluation dataset includes post-operative CT scans of a unipolar hemi-arthroplasty, a dynamic hip screw fixation, a bipolar hemi-arthroplasty, a fixation with cannulated screws and a total hip arthroplasty. All CT scans were analysed before and after processing with metal artefact removal software. Results Cortical thickness validity and accuracy were improved through the use of a modified metalwork-optimised model and metal artefact removal software. For the proximal femoral segments of the aforementioned cases, the cortical thickness was measured with a mean absolute error of 0.55, 0.39, 0.46, 0.53 and 0.69 mm. The hemi-pelvis produced thickness errors of 0.51, 0.52, 0.52, 0.47 and 0.67 mm, respectively. Conclusions The proposed method was shown to measure cortical bone thickness in the presence of metalwork at a sub-millimetre accuracy. This new technique might be helpful in assessing fracture healing near implants or fixation devices, and improve the evaluation of periprosthetic bone after hip replacement surgery.
dc.description.sponsorshipThis study was funded by Eli Lilly, Europe. TW, GMT, AHG and KESP received research grants from Eli Lilly. KESP is also funded by the Cambridge NIHR Biomedical Research Centre (BRC). The Evelyn Trust funded GMT.
dc.languageengen
dc.language.isoenen
dc.publisherSpringer
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectcomputed tomographyen
dc.subjectcortical thicknessen
dc.subjecthip implantsen
dc.subjectmetal artefact removalen
dc.titleAn exploratory study into measuring the cortical bone thickness from CT in the presence of metal implantsen
dc.typeArticle
prism.publicationDate2017en
prism.publicationNameInternational Journal of Computer Assisted Radiology and Surgeryen
dc.identifier.doi10.17863/CAM.9272
dcterms.dateAccepted2017-02-08en
rioxxterms.versionofrecord10.1007/s11548-017-1539-zen
rioxxterms.versionVoRen
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2017-02-23en
dc.contributor.orcidTreece, Graham [0000-0003-0047-6845]
dc.contributor.orcidPoole, Kenneth [0000-0003-4546-7352]
dc.identifier.eissn1861-6429
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idCambridge University Hospitals NHS Foundation Trust (CUH) (146281)
pubs.funder-project-idArthritis Research Uk (20109)


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International