Theses - MRC Cancer Unit
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Recent Submissions
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Development of a hydrogel-based microfluidic model of the lymph node
Lymph nodes (LNs) are immunological hubs where antigen and naïve lymphocytes meet to mount antigen specific immune responses. In cancers, the tumour-draining lymph node (TDLN) is the site of initial anti-tumour immune ... -
Resolving the evolution of Oesophageal Adenocarcinoma using spatial and temporal sampling
Introduction Oesophageal adenocarcinoma (OAC) remains a poor prognosis cancer type. The pre-malignant lesion for this type of cancer is called Barrett’s Oesophagus (BO), which has two subtypes, Gastric Metaplasia (GM) ... -
An Investigation of Mutational Signatures in the Evolution of Oesophageal adenocarcinoma
An Investigation of Mutational Signatures in the Evolution of Oesophageal adenocarcinoma Sujath Abbas Oesophageal adenocarcinoma (OAC) remains a public health challenge with dismal survival rates and increasing incidence. ...