Now showing items 1-4 of 64

    • Exploring the role of the unfolded protein response in C. elegans neurons 

      Ozbey, Nesem Petek (2019-12-04)
      The nervous system of C. elegans plays a role in the orchestration of systemic stress responses. One of these stress responses, the unfolded protein response of the endoplasmic reticulum (UPRER), is activated to re-establish ...
    • Molecular recognition of aberrant translation 

      Juszkiewicz, Szymon (2019-11-30)
      Protein translation is a fundamental, demanding process which requires several million ribosomes and consumes as much as 75% of cellular energy. Because of its importance, translation is regulated at many levels to maintain ...
    • Structural studies of trans-translation 

      Rae, Christopher (2019-10-26)
      Ribosomes translate messenger RNA (mRNA) into protein in all living cells. The faultless production of protein is critical for a vast array of catalytic and structural roles and is essential for the survival of the cell. ...
    • A screen for novel interactions within the vertebrate centriole 

      Barnabas, Deepak David (2019-09-30)
      The centrioles organize the centrosomes and cilia which play a role in cell division, motility, sensing, polarity, trafficking and signalling. There has been an increase in the understanding of centriole composition and ...