Theses - MRC Laboratory of Molecular Biology: Recent submissions
Now showing items 1-4 of 123
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The role of the histone variant H3.3 and its chaperones in the response to DNA damage
H3.3 is a histone variant without a clear, single function. Unlike the canonical replicationassociated H3.1 and H3.2, it is present throughout the cell cycle and can be deposited into chromatin by two distinct and specific ... -
The circuit basis of olfactory mate recognition and localisation
The circuit basis of olfactory mate recognition and localisation Finding a mate has two essential steps: recognising an appropriate partner and locating it. Sex pheromones are used in solving both tasks; they carry qualitative ... -
Molecular Architecture of the ER-Mitochondria Encounter Structure
Membrane contact sites (MCS) form between all organelles of eukaryotic cells and facilitate interdependent processes between unique subcellular compartments. In budding yeast, MCS between the endoplasmic reticulum (ER) and ... -
Regulation of Wnt signalling pathways by the Dishevelled DEP domain
Wnt signals bind to Frizzled receptors to trigger canonical and noncanonical signalling responses that control cell fates during animal development and tissue homeostasis. All Wnt signals are relayed by the hub protein ...
