Demystifying blood stem cell fates
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Hamey, FK
Göttgens, B
Abstract
Determining the differentiation potential of stem and progenitor cells is essential for understanding their function, yet our ability to do so is limited by the restrictions of experimental assays. Based on single-cell functional and molecular profiling experiments, a new computational approach shows how lineage commitment may occur in human haematopoiesis.
Description
Keywords
cell lineage, haematopoietic stem cells, stem-cell differentiation
Journal Title
Nature Cell Biology
Conference Name
Journal ISSN
1465-7392
1476-4679
1476-4679
Volume Title
19
Publisher
Nature Publishing Group
Publisher DOI
Sponsorship
Cancer Research UK (21762)
MRC (MR/K500975/1)
Leukaemia & Lymphoma Research (12029)
Medical Research Council (MC_PC_12009)
Medical Research Council (MR/M008975/1)
MRC (MR/K500975/1)
Leukaemia & Lymphoma Research (12029)
Medical Research Council (MC_PC_12009)
Medical Research Council (MR/M008975/1)