Demystifying blood stem cell fates
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Publication Date
2017-03-31Journal Title
Nature Cell Biology
ISSN
1465-7392
Publisher
Nature Publishing Group
Volume
19
Issue
4
Pages
261-263
Language
English
Type
Article
This Version
AM
Metadata
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Hamey, F., & Gottgens, B. (2017). Demystifying blood stem cell fates. Nature Cell Biology, 19 (4), 261-263. https://doi.org/10.1038/ncb3494
Abstract
Determining the differentiation potential of stem and progenitor cells is essential for understanding their function, yet our ability to do so is limited by the restrictions of experimental assays. Based on single-cell functional and molecular profiling experiments, a new computational approach shows how lineage commitment may occur in human haematopoiesis.
Keywords
cell lineage, haematopoietic stem cells, stem-cell differentiation
Sponsorship
Cancer Research UK (21762)
MRC (MR/K500975/1)
Leukaemia & Lymphoma Research (12029)
MRC (MC_PC_12009)
MEDICAL RESEARCH COUNCIL (MR/M008975/1)
Identifiers
External DOI: https://doi.org/10.1038/ncb3494
This record's URL: https://www.repository.cam.ac.uk/handle/1810/264438
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