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dc.contributor.authorPompa, Aen
dc.contributor.authorDe Marchis, Fen
dc.contributor.authorPallotta, MTen
dc.contributor.authorBenitez-Alfonso, Yen
dc.contributor.authorJones, Aen
dc.contributor.authorSchipper, Ken
dc.contributor.authorMoreau, Kevinen
dc.contributor.authorŽárský, Ven
dc.contributor.authorDi Sansebastiano, GPen
dc.contributor.authorBellucci, Men
dc.date.accessioned2017-06-15T09:51:33Z
dc.date.available2017-06-15T09:51:33Z
dc.date.issued2017-03-25en
dc.identifier.issn1661-6596
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/264779
dc.description.abstractMany proteins and cargoes in eukaryotic cells are secreted through the conventional secretory pathway that brings proteins and membranes from the endoplasmic reticulum to the plasma membrane, passing through various cell compartments, and then the extracellular space. The recent identification of an increasing number of leaderless secreted proteins bypassing the Golgi apparatus unveiled the existence of alternative protein secretion pathways. Moreover, other unconventional routes for secretion of soluble or transmembrane proteins with initial endoplasmic reticulum localization were identified. Furthermore, other proteins normally functioning in conventional membrane traffic or in the biogenesis of unique plant/fungi organelles or in plasmodesmata transport seem to be involved in unconventional secretory pathways. These alternative pathways are functionally related to biotic stress and development, and are becoming more and more important in cell biology studies in yeast, mammalian cells and in plants. The city of Lecce hosted specialists working on mammals, plants and microorganisms for the inaugural meeting on "Unconventional Protein and Membrane Traffic" (UPMT) during 4-7 October 2016. The main aim of the meeting was to include the highest number of topics, summarized in this report, related to the unconventional transport routes of protein and membranes.
dc.description.sponsorshipThe UPMT committee is grateful to the sponsors supporting the meeting: The Company of Biologists, Fondazione Puglia, the American Society of Plant Biologists, the Biochemical Society, University of Salento, CNR-Nanotec, MDPI-International Journal of Molecular Science and Merck.
dc.languageengen
dc.language.isoenen
dc.publisherMDPI AG
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectautophagyen
dc.subjectexosomesen
dc.subjectintercellular channelsen
dc.subjectleaderless proteinsen
dc.subjectprotein secretionen
dc.subjecttrafficking mechanismsen
dc.subjectunconventional secretionen
dc.subjectanimalsen
dc.subjectcell biologyen
dc.subjectdevelopmental biologyen
dc.subjecthumansen
dc.subjectmembrane proteinsen
dc.subjectprotein transporten
dc.titleUnconventional Transport Routes of Soluble and Membrane Proteins and Their Role in Developmental Biologyen
dc.typeArticle
prism.issueIdentifier4en
prism.number703en
prism.publicationDate2017en
prism.publicationNameInternational Journal of Molecular Sciencesen
prism.volume18en
dc.identifier.doi10.17863/CAM.10470
dcterms.dateAccepted2017-03-23en
rioxxterms.versionofrecord10.3390/ijms18040703en
rioxxterms.versionVoRen
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2017-03-25en
dc.contributor.orcidMoreau, Kevin [0000-0002-3688-3998]
dc.identifier.eissn1422-0067
rioxxterms.typeJournal Article/Reviewen


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International