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Exposure of patients to ionising radiation during lung cancer diagnostic work-up

Accepted version
Peer-reviewed

Type

Article

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Authors

Rintoul, RC 
Atherton, R 
Tweed, K 
Yates, S 
Chilvers, ER 

Abstract

We examined the dose of radiation received during diagnosis of lung cancer as this may add to the risk of a second primary cancer. Patients undergoing surgery (n=40) or (chemo)radiotherapy (n=40) received comparable doses (28.6 and 25.8 mSv, respectively), significantly higher than that for supportive care (n=40; 15.1 mSv). The effective dose of radiation received was higher for early stage disease than for those with metastatic disease. The mean lifetime attributable risk of malignancy for those receiving treatment with curative intent in our cohort was 0.059%, and lung-specific risk 0.019%.

Description

Keywords

imaging/CT MRI etc, lung cancer

Journal Title

Thorax

Conference Name

Journal ISSN

0040-6376
1468-3296

Volume Title

Publisher

BMJ Publishing
Sponsorship
Medical Research Council (MR/J00345X/1)
RCR is part funded by the Cambridge Biomedical Research Centre.