Exposure of patients to ionising radiation during lung cancer diagnostic work-up
Accepted version
Peer-reviewed
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Authors
Rintoul, RC
Atherton, R
Tweed, K
Yates, S
Chilvers, ER
Abstract
We examined the dose of radiation received during diagnosis of lung cancer as this may add to the risk of a second primary cancer. Patients undergoing surgery (n=40) or (chemo)radiotherapy (n=40) received comparable doses (28.6 and 25.8 mSv, respectively), significantly higher than that for supportive care (n=40; 15.1 mSv). The effective dose of radiation received was higher for early stage disease than for those with metastatic disease. The mean lifetime attributable risk of malignancy for those receiving treatment with curative intent in our cohort was 0.059%, and lung-specific risk 0.019%.
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Keywords
imaging/CT MRI etc, lung cancer
Journal Title
Thorax
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Journal ISSN
0040-6376
1468-3296
1468-3296
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Publisher
BMJ Publishing
Publisher DOI
Sponsorship
Medical Research Council (MR/J00345X/1)
RCR is part funded by the Cambridge Biomedical Research Centre.