The Test Your Memory for Mild Cognitive Impairment (TYM-MCI)
Journal of Neurology, Neurosurgery and Psychiatry
BMJ Publishing Group
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Brown, J., Lansdall, C., Wiggins, J., Dawson, K., Hunter, K., Rowe, J. B., & Parker, R. (2017). The Test Your Memory for Mild Cognitive Impairment (TYM-MCI). Journal of Neurology, Neurosurgery and Psychiatry https://doi.org/10.1136/jnnp-2016-315327
BACKGROUND: To validate a short cognitive test: the Test Your Memory for Mild Cognitive Impairment (TYM-MCI) in the diagnosis of patients with amnestic mild cognitive impairment or mild Alzheimer’s disease (aMCI/AD). METHODS: Two hundred and two patients with mild memory problems were recruited. All had ‘passed’ the Mini-Mental State Examination (MMSE). Patients completed the TYM-MCI, the Test Your Memory test (TYM), MMSE and revised Addenbrooke’s Cognitive Examination (ACE-R), had a neurological examination, clinical diagnostics and multidisciplinary team review. RESULTS: As a single test, the TYM-MCI performed as well as the ACE-R in the distinction of patients with aMCI/AD from patients with subjective memory impairment with a sensitivity of 0.79 and specificity of 0.91. Used in combination with the ACE-R, it provided additional value and identified almost all cases of aMCI/AD. The TYM-MCI correctly classified most patients who had equivocal ACE-R scores. Integrated discriminant improvement analysis showed that the TYM-MCI added value to the conventional memory assessment. Patients initially diagnosed as unknown or with subjective memory impairment who were later rediagnosed with aMCI/AD scored poorly on their original TYM-MCI. CONCLUSION: The TYM-MCI is a powerful short cognitive test that examines verbal and visual recall and is a valuable addition to the assessment of patients with aMCI/AD. It is simple and cheap to administer and requires minimal staff time and training.
TYM-MCI, TYM, Alzheimer’s disease, amnestic Mild Cognitive Impairment, cognition
JBR was supported by the Wellcome Trust (103838).
Wellcome Trust (103838/Z/14/Z)
Embargo Lift Date
External DOI: https://doi.org/10.1136/jnnp-2016-315327
This record's URL: https://www.repository.cam.ac.uk/handle/1810/266052
Attribution 4.0 International
Licence URL: http://creativecommons.org/licenses/by/4.0/