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Synthetic scaffolds help airway cells reach maturity

Published version
Peer-reviewed

Type

Article

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Authors

Nikolić, MZ 
Rawlins, EL 

Abstract

Transplanting bioengineered human lung organoids into mice could lead to a humanized model for pre-clinical studies of lung disease.

Description

Keywords

developmental biology, human pluripotent stem cells, lung airway, mouse, organoids, scaffolds, stem cells, transplantation, Animals, Cell Differentiation, Humans, Lung, Mice, Organoids, Pluripotent Stem Cells

Journal Title

eLife

Conference Name

Journal ISSN

2050-084X
2050-084X

Volume Title

5

Publisher

eLife Sciences Publications Ltd
Sponsorship
Medical Research Council (G0900424)
Wellcome Trust (092096/Z/10/Z)
Wellcome Trust (100677/Z/12/Z)
Wellcome Trust (100677/Z/12/A)
Wellcome Trust (105602/Z/14/Z)
Addenbrooke's Charitable Trust (ACT) (1646)