Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy
De Lucia Rolfe, Emanuella
Hughes, Ieuan A.
Dunger, David B.
Stolk, Ronald P.
Ong, Ken K.
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De Lucia Rolfe, E., Modi, N., Uthaya, S., Hughes, I. A., Dunger, . B., Acerini, C., Stolk, R. P., & et al. (2013). Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy. https://doi.org/10.1155/2013/951954
Other imaging techniques to quantify internal-abdominal adiposity (IA-AT) and subcutaneous-abdominal adiposity (SCA-AT) are frequently impractical in infants. The aim of this study was twofold: (a) to validate ultrasound (US) visceral and subcutaneous-abdominal depths in assessing IA-AT and SCA-AT from MRI as the reference method in infants and (b) to analyze the association between US abdominal adiposity and anthropometric measures at ages 3 months and 12 months. Twenty-two infants underwent MRI and US measures of abdominal adiposity. Abdominal US parameters and anthropometric variables were assessed in the Cambridge Baby Growth Study (CBGS), infants (23 girls) at age 3 months and infants (237 girls) at 12 months. US visceral and subcutaneous-abdominal depths correlated with MRI quantified IA-AT (, ) and SCA-AT (, ) volumes, respectively. In CBGS, mean US-visceral depths increased by 20 % between ages 3 and 12 months () and at both ages were lower in infants breast-fed at 3 months than in other infants. US-visceral depths at both 3 and 12 months were inversely related to skinfold thickness at birth ( and at 3 and 12 months, resp.; adjusted for current skinfold thickness). In contrast, US-subcutaneous-abdominal depth at 3 months was positively related to skinfold thickness at birth (). US measures can rank infants with higher or lower IA-AT and SCA-AT. Contrasting patterns of association with visceral and subcutaneous-abdominal adiposities indicate that they may be differentially regulated in infancy.
External DOI: https://doi.org/10.1155/2013/951954
This record's URL: https://www.repository.cam.ac.uk/handle/1810/267613
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Rights Holder: Copyright © 2013 Emanuella De Lucia Rolfe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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