Show simple item record

dc.contributor.authorDe Lucia Rolfe, Emanuella
dc.contributor.authorModi, Neena
dc.contributor.authorUthaya, Sabita
dc.contributor.authorHughes, Ieuan
dc.contributor.authorDunger, David
dc.contributor.authorAcerini, Carlo
dc.contributor.authorStolk, Ronald P
dc.contributor.authorOng, Kenneth
dc.date.accessioned2017-10-03T07:44:58Z
dc.date.available2017-10-03T07:44:58Z
dc.date.issued2013
dc.identifier.citationEmanuella De Lucia Rolfe, Neena Modi, Sabita Uthaya, et al., “Ultrasound Estimates of Visceral and Subcutaneous-Abdominal Adipose Tissues in Infancy,” Journal of Obesity, vol. 2013, Article ID 951954, 9 pages, 2013. doi:10.1155/2013/951954
dc.identifier.issn2090-0708
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/267613
dc.description.abstractOther imaging techniques to quantify internal-abdominal adiposity (IA-AT) and subcutaneous-abdominal adiposity (SCA-AT) are frequently impractical in infants. The aim of this study was twofold: (a) to validate ultrasound (US) visceral and subcutaneous-abdominal depths in assessing IA-AT and SCA-AT from MRI as the reference method in infants and (b) to analyze the association between US abdominal adiposity and anthropometric measures at ages 3 months and 12 months. Twenty-two infants underwent MRI and US measures of abdominal adiposity. Abdominal US parameters and anthropometric variables were assessed in the Cambridge Baby Growth Study (CBGS), n = 487 infants (23 girls) at age 3 months and n = 495 infants (237 girls) at 12 months. US visceral and subcutaneous-abdominal depths correlated with MRI quantified IA-AT (r = 0.48, P < 0.05) and SCA-AT (r = 0.71, P < 0.001) volumes, respectively. In CBGS, mean US-visceral depths increased by ~20 % between ages 3 and 12 months (P < 0.0001) and at both ages were lower in infants breast-fed at 3 months than in other infants. US-visceral depths at both 3 and 12 months were inversely related to skinfold thickness at birth (P = 0.03 and P = 0.009 at 3 and 12 months, resp.; adjusted for current skinfold thickness). In contrast, US-subcutaneous-abdominal depth at 3 months was positively related to skinfold thickness at birth (P = 0.004). US measures can rank infants with higher or lower IA-AT and SCA-AT. Contrasting patterns of association with visceral and subcutaneous-abdominal adiposities indicate that they may be differentially regulated in infancy.
dc.publisherHindawi Limited
dc.rightsAll Rights Reserved
dc.rights.urihttps://www.rioxx.net/licenses/all-rights-reserved/
dc.titleUltrasound estimates of visceral and subcutaneous-abdominal adipose tissues in infancy.
dc.typeArticle
dc.date.updated2017-07-13T08:33:39Z
dc.description.versionPeer Reviewed
dc.language.rfc3066en
dc.rights.holderCopyright © 2013 Emanuella De Lucia Rolfe et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
prism.publicationNameJ Obes
dc.identifier.doi10.17863/CAM.13552
dcterms.dateAccepted2013-03-27
rioxxterms.versionofrecord10.1155/2013/951954
dc.contributor.orcidDe Lucia Rolfe, Emanuella [0000-0003-3542-2767]
dc.contributor.orcidDunger, David [0000-0002-2566-9304]
dc.contributor.orcidAcerini, Carlo [0000-0003-2121-5871]
dc.contributor.orcidOng, Kenneth [0000-0003-4689-7530]
dc.identifier.eissn2090-0716
pubs.funder-project-idNational Institute for Health Research (NIHR) (via West Anglia Comprehensive Local Research Network (CLRN)) (UKCRN 11822)
pubs.funder-project-idNational Institute for Health Research (NIHR) via Comprehensive Local Research Network (CLRN) (UKCRN 15224)
pubs.funder-project-idNational Institute for Health Research (NIHR) (via West Anglia Comprehensive Local Research Network (CLRN)) (11822)
pubs.funder-project-idMedical Research Council (G0600717)
pubs.funder-project-idMedical Research Council (MC_UU_12015/2)
pubs.funder-project-idMedical Research Council (MC_U106179472)


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record