Hepatorenal Syndrome: Aetiology, Diagnosis, and Treatment
Alexander, G. J. M.
Lomas, D. J.
MetadataShow full item record
Low, G., Alexander, G. J. M., & Lomas, D. J. (2015). Hepatorenal Syndrome: Aetiology, Diagnosis, and Treatment. https://doi.org/10.1155/2015/207012
Acute renal impairment is common in patients with chronic liver disease, occurring in approximately 19% of hospitalised patients with cirrhosis. A variety of types of renal impairment are recognised. The most important of these is the hepatorenal syndrome, a functional renal impairment due to circulatory and neurohormonal abnormalities that underpin cirrhosis. It is one of the most severe complications of cirrhosis with survival often measured in weeks to months. A variety of treatment options exist with early diagnosis and appropriate treatment providing the best hope for cure. This paper provides a comprehensive and up-to-date review of hepatorenal syndrome and lays out the topic according to the following sections: pathophysiology, historical developments, diagnostic criteria and limitations, epidemiology, precipitating factors, predictors, clinical and laboratory findings, prognosis, treatment options, prophylaxis, and conclusion.
External DOI: https://doi.org/10.1155/2015/207012
This record's URL: https://www.repository.cam.ac.uk/handle/1810/267634
All Rights Reserved
Rights Holder: Copyright © 2015 G. Low et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Licence URL: https://www.rioxx.net/licenses/all-rights-reserved/