This paper applies the principles of Input Output Analysis (IOA) to identify key structural dependencies between the pharmaceutical sector, the digital sectors, and all the other sectors in an economy. The computation and visualisation of selected metrics to evaluate the strength of downstream and upstream economic connectedness of the digital and pharmaceutical sec-tors is demonstrated using digital data collections for the UK national economy. Although the analysis is limited to a single-country and a single reference year for illustrative purposes, the proposed approach is meant to provide a bird’s-eye view on how the networked structure of the economic system determines paths of influence between the sectors of interests. Such a top-level view is meant to inform and complement the assessment of individual technology interventions of relevance for the ‘digitisation’ of end-to-end pharmaceutical supply chains