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dc.contributor.authorCantacessi, Cinziaen
dc.contributor.authorParadies, Pen
dc.contributor.authorIarussi, Fen
dc.contributor.authorSasanelli, Men
dc.contributor.authorCapogna, Aen
dc.contributor.authorZucca, Den
dc.contributor.authorGreco, Ben
dc.contributor.authorOtranto, Den
dc.date.accessioned2017-09-01T12:38:59Z
dc.date.accessioned2017-11-08T16:37:09Z
dc.date.available2017-09-01T12:38:59Z
dc.date.available2017-11-08T16:37:09Z
dc.date.issued2017-07-20en
dc.identifier.issn1756-3305
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/268188
dc.description.abstractBackground The increasing number of reports of human infections by Strongyloides stercoralis from a range of European countries over the last 20 years has spurred the interest of the scientific community towards this parasite and, in particular, towards the role that infections of canine hosts may play in the epidemiology of human disease. Data on the epidemiology of canine strongyloidiasis is currently limited, most likely because of the inherent limitations of current diagnostic methods. Methods Faecal samples were collected directly from the rectal ampulla of 272 animals of varying age and both genders living in Apulia, southern Italy. Dogs included were either privately owned (n = 210), living in an urban area but with unrestricted outdoor access (Group 1), or shelter dogs (n = 62 out of ~400) hosted in a single shelter in the province of Bari in which a history of diarrhoea, weight loss, reduced appetite and respiratory symptoms had been reported (Group 2). Strongyloides stercoralis infection was diagnosed by coproscopy on direct faecal smear and via the Baermann method. Results Six of 272 dogs were positive for S. stercoralis at the Baermann examination; all but one were from the shelter (Group 2) and displayed gastrointestinal clinical signs. The only owned dog (Group 1) infected with S. stercoralis, but clinically healthy, had been adopted from a shelter 1 year prior to sampling. Five infected dogs were treated with fenbendazole (Panacur®, Intervet, Animal Health, 50 mg/kg, PO daily for 5 days), or with a combination of fenbendazole and moxidectin plus imidacloprid spot-on (Im/Mox; Advocate® spot-on, Bayer). Post-treatment clearance of infection was confirmed in three dogs by Baermann examination, whereas treatment failure was documented in two dogs by Baermann and/or post-mortem detection of adult parasites. Conclusions This study describes, for the first time, the presence of S. stercoralis infection in sheltered dogs from southern Italy. Data indicate that S. stercoralis infection may pose a concern for sheltered animals and raise questions on potential risks of infection for staff of municipal shelters in southern European countries. Given that a single course of treatment with fenbendazole, associated or not with Im/Mox spot-on, may not eliminate the infection, effective treatment protocols should be investigated and control strategies targeting the environment considered for reducing the risk of zoonotic infection.
dc.language.isoenen
dc.publisherBioMed Central
dc.relation.replaceshttps://www.repository.cam.ac.uk/handle/1810/266992
dc.relation.replaces1810/266992
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rightsAttribution 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectstrongyloides stercoralisen
dc.subjectzoonosisen
dc.subjecttreatmenten
dc.subjectfaecal monitoringen
dc.subjectdogen
dc.subjectclinical presentationen
dc.titleOccurrence of strongyloidiasis in privately owned and sheltered dogs - clinical presentation and treatment outcomeen
dc.typeArticle
prism.issueIdentifier345en
prism.publicationDate2017en
prism.publicationNameParasites & Vectorsen
prism.volume10en
dc.identifier.doi10.17863/CAM.13028
dc.identifier.doi10.17863/CAM.14389
dcterms.dateAccepted2017-07-05en
rioxxterms.versionofrecord10.1186/s13071-017-2275-5en
rioxxterms.versionVoRen
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2017-07-20en
dc.contributor.orcidCantacessi, Cinzia [0000-0001-6863-2950]
dc.identifier.eissn1756-3305
rioxxterms.typeJournal Article/Reviewen
cam.issuedOnline2017-07-20en


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International