Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.

Kilpeläinen, Tuomas O; Qi, Lu; Brage, Soren; Sharp, Stephen John; Sonestedt, Emily; Demerath, Ellen; Ahmad, Tariq; Mora, Samia; Kaakinen, Marika; Sandholt, Camilla Helene; Holzapfel, Christina; Autenrieth, Christine S; Hyppönen, Elina; Cauchi, Stéphane; He, Meian; Kutalik, Zoltan; Kumari, Meena; Stančáková, Alena; Meidtner, Karina; Balkau, Beverley; Tan, Jonathan T; Mangino, Massimo; Timpson, Nicholas J; Song, Yiqing; Zillikens, M Carola; Jablonski, Kathleen A; Garcia, Melissa E; Johansson, Stefan; Bragg-Gresham, Jennifer L; Wu, Ying; van Vliet-Ostaptchouk, Jana V; Onland-Moret, N Charlotte; Zimmermann, Esther; Rivera, Natalia V; Tanaka, Toshiko; Stringham, Heather M; Silbernagel, Günther; Kanoni, Stavroula; Feitosa, Mary F; Snitker, Soren; Ruiz, Jonatan R; Metter, Jeffery; Larrad, Maria Teresa Martinez; Atalay, Mustafa; Hakanen, Maarit; Amin, Najaf; Cavalcanti-Proença, Christine; Grøntved, Anders; Hallmans, Göran; Jansson, John-Olov; Kuusisto, Johanna; Kähönen, Mika; Lutsey, Pamela L; Nolan, John J; Palla, Luigi; Pedersen, Oluf; Pérusse, Louis; Renström, Frida; Scott, Robert; Shungin, Dmitry; Sovio, Ulla Maarit; Tammelin, Tuija H; Rönnemaa, Tapani; Lakka, Timo A; Uusitupa, Matti; Rios, Manuel Serrano; Ferrucci, Luigi; Bouchard, Claude; Meirhaeghe, Aline; Fu, Mao; Walker, Mark; Borecki, Ingrid B; Dedoussis, George V; Fritsche, Andreas; Ohlsson, Claes; Boehnke, Michael; Bandinelli, Stefania; van Duijn, Cornelia M; Ebrahim, Shah; Lawlor, Debbie A; Gudnason, Vilmundur; Harris, Tamara B; Sørensen, Thorkild IA; Mohlke, Karen L; Hofman, Albert; Uitterlinden, André G; Tuomilehto, Jaakko; Lehtimäki, Terho; Raitakari, Olli; Isomaa, Bo; Njølstad, Pål R; Florez, Jose C; Liu, Simin; Ness, Andy; Spector, Timothy D; Tai, E Shyong; Froguel, Philippe; Boeing, Heiner; Laakso, Markku; Marmot, Michael; Bergmann, Sven; Power, Chris; Khaw, Kay-Tee; Chasman, Daniel; Ridker, Paul; Hansen, Torben; Monda, Keri L; Illig, Thomas; Järvelin, Marjo-Riitta; Wareham, Nicholas John; Hu, Frank B; Groop, Leif C; Orho-Melander, Marju; Ekelund, Ulf Mikael; Franks, Paul W; Loos, Ruth JF

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Authors

Kilpeläinen, Tuomas O

Qi, Lu

Brage, Soren

Sharp, Stephen John

Sonestedt, Emily

Demerath, Ellen

Ahmad, Tariq

Publication Date

2011-11

Journal Title

PLoS medicine

ISSN

1549-1277

Volume

Issue

Pages

e1001116

Language

eng

Type

Article

This Version

VoR

Physical Medium

Print-Electronic

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Citation

Kilpeläinen, T. O., Qi, L., Brage, S., Sharp, S. J., Sonestedt, E., Demerath, E., Ahmad, T., et al. (2011). Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.. PLoS medicine, 8 (11), e1001116. https://doi.org/10.1371/journal.pmed.1001116

Keywords

Adipose Tissue, Humans, Obesity, Genetic Predisposition to Disease, Proteins, Risk Factors, Motor Activity, Genotype, Polymorphism, Single Nucleotide, Adolescent, Adult, Aged, Child, Female, Male, Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Sponsorship

Medical Research Council (G1000143)

Medical Research Council (G0401527)

Medical Research Council (MC_UU_12015/1)

Medical Research Council (MC_UU_12015/3)

Medical Research Council (G0701863)

Medical Research Council (MC_U106188470)

Identifiers

External DOI: https://doi.org/10.1371/journal.pmed.1001116

This record's URL: https://www.repository.cam.ac.uk/handle/1810/269342

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Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International

Licence URL: http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/

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Except where otherwise noted, this item's licence is described as Attribution 4.0 International