Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.

Kilpeläinen, Tuomas O; Qi, Lu; Brage, Soren; Sharp, Stephen; Sonestedt, Emily; Demerath, Ellen; Ahmad, Tariq; Mora, Samia; Kaakinen, Marika; Sandholt, Camilla Helene; Holzapfel, Christina; Autenrieth, Christine S; Hyppönen, Elina; Cauchi, Stéphane; He, Meian; Kutalik, Zoltan; Kumari, Meena; Stančáková, Alena; Meidtner, Karina; Balkau, Beverley; Tan, Jonathan T; Mangino, Massimo; Timpson, Nicholas J; Song, Yiqing; Zillikens, M Carola; Jablonski, Kathleen A; Garcia, Melissa E; Johansson, Stefan; Bragg-Gresham, Jennifer L; Wu, Ying; van Vliet-Ostaptchouk, Jana V; Onland-Moret, N Charlotte; Zimmermann, Esther; Rivera, Natalia V; Tanaka, Toshiko; Stringham, Heather M; Silbernagel, Günther; Kanoni, Stavroula; Feitosa, Mary F; Snitker, Soren; Ruiz, Jonatan R; Metter, Jeffery; Larrad, Maria Teresa Martinez; Atalay, Mustafa; Hakanen, Maarit; Amin, Najaf; Cavalcanti-Proença, Christine; Grøntved, Anders; Hallmans, Göran; Jansson, John-Olov; Kuusisto, Johanna; Kähönen, Mika; Lutsey, Pamela L; Nolan, John J; Palla, Luigi; Pedersen, Oluf; Pérusse, Louis; Renström, Frida; Scott, Robert; Shungin, Dmitry; Sovio, Ulla; Tammelin, Tuija H; Rönnemaa, Tapani; Lakka, Timo A; Uusitupa, Matti; Rios, Manuel Serrano; Ferrucci, Luigi; Bouchard, Claude; Meirhaeghe, Aline; Fu, Mao; Walker, Mark; Borecki, Ingrid B; Dedoussis, George V; Fritsche, Andreas; Ohlsson, Claes; Boehnke, Michael; Bandinelli, Stefania; van Duijn, Cornelia M; Ebrahim, Shah; Lawlor, Debbie A; Gudnason, Vilmundur; Harris, Tamara B; Sørensen, Thorkild IA; Mohlke, Karen L; Hofman, Albert; Uitterlinden, André G; Tuomilehto, Jaakko; Lehtimäki, Terho; Raitakari, Olli; Isomaa, Bo; Njølstad, Pål R; Florez, Jose C; Liu, Simin; Ness, Andy; Spector, Timothy D; Tai, E Shyong; Froguel, Philippe; Boeing, Heiner; Laakso, Markku; Marmot, Michael; Bergmann, Sven; Power, Chris; Khaw, Kay-Tee; Chasman, Daniel; Ridker, Paul; Hansen, Torben; Monda, Keri L; Illig, Thomas; Järvelin, Marjo-Riitta; Wareham, Nicholas; Hu, Frank B; Groop, Leif C; Orho-Melander, Marju; Ekelund, Ulf; Franks, Paul W; Loos, Ruth JF

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Authors

Kilpeläinen, Tuomas O

Qi, Lu

Brage, Soren

Sharp, Stephen

Sonestedt, Emily

Demerath, Ellen

Ahmad, Tariq

Publication Date

2011-11

Journal Title

PLoS medicine

ISSN

1549-1277

Volume

Issue

Pages

e1001116

Language

eng

Type

Article

This Version

VoR

Physical Medium

Print-Electronic

Metadata

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Citation

Kilpeläinen, T. O., Qi, L., Brage, S., Sharp, S., Sonestedt, E., Demerath, E., Ahmad, T., et al. (2011). Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children.. PLoS medicine, 8 (11), e1001116. https://doi.org/10.1371/journal.pmed.1001116

Keywords

Adipose Tissue, Humans, Obesity, Genetic Predisposition to Disease, Proteins, Risk Factors, Motor Activity, Genotype, Polymorphism, Single Nucleotide, Adolescent, Adult, Aged, Child, Female, Male, Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Sponsorship

MRC (G0401527)

MRC (G1000143)

Medical Research Council (G0701863)

MEDICAL RESEARCH COUNCIL (MC_U106188470)

MRC (MC_UU_12015/1)

MRC (MC_UU_12015/3)

Medical Research Council (MC_U106179471)

Identifiers

External DOI: https://doi.org/10.1371/journal.pmed.1001116

This record's URL: https://www.repository.cam.ac.uk/handle/1810/269342

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Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International

Licence URL: http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/

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Except where otherwise noted, this item's licence is described as Attribution 4.0 International