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A novel community driven software for functional enrichment analysis of extracellular vesicles data.

Published version
Peer-reviewed

Type

Article

Change log

Authors

Pathan, Mohashin 
Keerthikumar, Shivakumar 
Chisanga, David 
Alessandro, Riccardo 
Ang, Ching-Seng 

Abstract

Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture "what the community needs in a tool". Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.

Description

Keywords

Extracellular vesicles, FunRich, bioinformatics

Journal Title

J Extracell Vesicles

Conference Name

Journal ISSN

2001-3078
2001-3078

Volume Title

6

Publisher

Wiley
Sponsorship
Medical Research Council (MC_PC_12009)