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A quantitative, multi-national and multi-stakeholder assessment of barriers to the adoption of cell therapies

Accepted version
Peer-reviewed

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Authors

Davies, BM 
Smith, J 
Rikabi, S 
Wartolowska, K 
Morrey, M 

Abstract

Cellular therapies, such as stem cell based treatments, have been widely researched and numerous products and treatments have been developed. Despite this, there has been relatively limited use of these technologies in the healthcare sector. This study sought to investigate the perceived barriers to this more widespread adoption. An anonymous online questionnaire was developed, based on the findings of a pilot study. This was distributed to an audience of clinicians, researchers, and commercial experts in 13 countries. The results were analysed for all respondents, and also sub-grouped by geographical region, and by profession of respondents. The results of the study showed that the most significant barrier was manufacturing, with other factors such as efficacy, regulation, and cost-effectiveness being identified by the different groups. This study further demonstrates the need for these important issues to be addressed during the development of cellular therapies to enable more widespread adoption of these treatments.

Description

Keywords

Cell- and tissue-based therapy, clinical adoption, regenerative medicine, stem cells, translational medical research

Journal Title

Journal of Tissue Engineering

Conference Name

Journal ISSN

2041-7314
2041-7314

Volume Title

8

Publisher

SAGE Publications
Sponsorship
JS is funded by an MRC UK Studentship.