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dc.contributor.authorMaas, Andrew IRen
dc.contributor.authorMenon, Daviden
dc.contributor.authorAdelson, P Daviden
dc.contributor.authorAndelic, Nadaen
dc.contributor.authorBell, Michael Jen
dc.contributor.authorBelli, Antonioen
dc.contributor.authorBragge, Peteren
dc.contributor.authorBrazinova, Alexandraen
dc.contributor.authorBüki, Andrásen
dc.contributor.authorChesnut, Randall Men
dc.contributor.authorCiterio, Giuseppeen
dc.contributor.authorCoburn, Marken
dc.contributor.authorCooper, D Jamieen
dc.contributor.authorCrowder, A Tamaraen
dc.contributor.authorCzeiter, Endreen
dc.contributor.authorCzosnyka, Mareken
dc.contributor.authorDiaz-Arrastia, Ramonen
dc.contributor.authorDreier, Jens Pen
dc.contributor.authorDuhaime, Ann-Christineen
dc.contributor.authorErcole, Arien
dc.contributor.authorvan Essen, Thomas Aen
dc.contributor.authorFeigin, Valery Len
dc.contributor.authorGao, Guoyien
dc.contributor.authorGiacino, Josephen
dc.contributor.authorGonzalez-Lara, Laura Een
dc.contributor.authorGruen, Russell Len
dc.contributor.authorGupta, Deepaken
dc.contributor.authorHartings, Jed Aen
dc.contributor.authorHill, Seanen
dc.contributor.authorJiang, Ji-Yaoen
dc.contributor.authorKetharanathan, Naomien
dc.contributor.authorKompanje, Erwin JOen
dc.contributor.authorLanyon, Lindaen
dc.contributor.authorLaureys, Stevenen
dc.contributor.authorLecky, Fionaen
dc.contributor.authorLevin, Harveyen
dc.contributor.authorLingsma, Hester Fen
dc.contributor.authorMaegele, Marcen
dc.contributor.authorMajdan, Mareken
dc.contributor.authorManley, Geoffreyen
dc.contributor.authorMarsteller, Jillen
dc.contributor.authorMascia, Lucianaen
dc.contributor.authorMcFadyen, Charlesen
dc.contributor.authorMondello, Stefaniaen
dc.contributor.authorNewcombe, Virginiaen
dc.contributor.authorPalotie, Aarnoen
dc.contributor.authorParizel, Paul Men
dc.contributor.authorPeul, Wilcoen
dc.contributor.authorPiercy, Jamesen
dc.contributor.authorPolinder, Suzanneen
dc.contributor.authorPuybasset, Louisen
dc.contributor.authorRasmussen, Todd Een
dc.contributor.authorRossaint, Rolfen
dc.contributor.authorSmielewski, Peteren
dc.contributor.authorSöderberg, Jeannetteen
dc.contributor.authorStanworth, Simon Jen
dc.contributor.authorStein, Murray Ben
dc.contributor.authorvon Steinbüchel, Nicoleen
dc.contributor.authorStewart, Williamen
dc.contributor.authorSteyerberg, Ewout Wen
dc.contributor.authorStocchetti, Ninoen
dc.contributor.authorSynnot, Annelieseen
dc.contributor.authorTe Ao, Bradenen
dc.contributor.authorTenovuo, Ollien
dc.contributor.authorTheadom, Aliceen
dc.contributor.authorTibboel, Dicken
dc.contributor.authorVidetta, Walteren
dc.contributor.authorWang, Kevin KWen
dc.contributor.authorWilliams, W Huwen
dc.contributor.authorWilson, Lindsayen
dc.contributor.authorYaffe, Kristineen
dc.contributor.authorInTBIR Participants and Investigators,en
dc.date.accessioned2018-01-31T12:50:06Z
dc.date.available2018-01-31T12:50:06Z
dc.date.issued2017-12-01en
dc.identifier.issn1474-4422
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/271382
dc.description.abstractA concerted effort to tackle the global health problem posed by traumatic brain injury (TBI) is long overdue. TBI is a public health challenge of vast, but insufficiently recognised, proportions. Worldwide, more than 50 million people have a TBI each year, and it is estimated that about half the world's population will have one or more TBIs over their lifetime. TBI is the leading cause of mortality in young adults and a major cause of death and disability across all ages in all countries, with a disproportionate burden of disability and death occurring in low-income and middle-income countries (LMICs). It has been estimated that TBI costs the global economy approximately $US400 billion annually. Deficiencies in prevention, care, and research urgently need to be addressed to reduce the huge burden and societal costs of TBI. This Commission highlights priorities and provides expert recommendations for all stakeholders—policy makers, funders, health-care professionals, researchers, and patient representatives—on clinical and research strategies to reduce this growing public health problem and improve the lives of people with TBI.
dc.description.sponsorshipWe acknowledge the support provided by the funding agencies joined in the InTBIR initiative: the Canadian Institutes of Health Research, the European Commission, the US National Institutes of Health-National Institute of Neurological Disorders and Stroke, One Mind, and the US Department of Defense. Additional support for Canadian studies within InTBIR was provided by Fonds de recherche du Québec Santé, the Hotchkiss Brain Institute, the Ontario Brain Institute, and the Ontario Neurotrauma Foundation. The Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) project received additional support from the Hannelore Kohl Stiftung, Germany. Synergistic funding for the Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) study was obtained through a successful application for a TBI Endpoints Development award from the US Department of Defense. In addition, DKM was supported through a Senior Investigator Award and funding for the Cambridge Biomedical Research Centre from the UK National Institute for Health Research.
dc.languageengen
dc.publisherElsevier
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.titleTraumatic brain injury: integrated approaches to improve prevention, clinical care, and research.en
dc.typeArticle
prism.endingPage1048
prism.issueIdentifier12en
prism.publicationDate2017en
prism.publicationNameThe Lancet Neurologyen
prism.startingPage987
prism.volume16en
dc.identifier.doi10.17863/CAM.18371
dcterms.dateAccepted2017-09-27en
rioxxterms.versionofrecord10.1016/S1474-4422(17)30371-Xen
rioxxterms.versionAM*
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
rioxxterms.licenseref.startdate2017-12-01en
dc.contributor.orcidMenon, David [0000-0002-3228-9692]
dc.contributor.orcidCzosnyka, Marek [0000-0003-2446-8006]
dc.contributor.orcidErcole, Ari [0000-0001-8350-8093]
dc.contributor.orcidNewcombe, Virginia [0000-0001-6044-9035]
dc.contributor.orcidSmielewski, Peter [0000-0001-5096-3938]
dc.identifier.eissn1474-4465
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idEC FP7 CP (602150)
pubs.funder-project-idMRC (G0601025)
pubs.funder-project-idMRC (G0600986)
cam.issuedOnline2017-11-06en
rioxxterms.freetoread.startdate2018-06-01


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International