Research data supporting "A fragment-based approach to targeting IMPDH from Mycobacterium tuberculosis"
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Authors
Trapero, Ana
Paccito, Angela
Singh, Vinayak
Sabbah, Mohamad
Mizrahi, Valerie
Ascher, David
Publication Date
2018-02-24Type
Dataset
Metadata
Show full item recordCitation
Trapero, A., Paccito, A., Singh, V., Sabbah, M., Coyne, A., Mizrahi, V., Blundell, T., et al. (2018). Research data supporting "A fragment-based approach to targeting IMPDH from Mycobacterium tuberculosis" [Dataset]. https://doi.org/10.17863/CAM.20512
Description
Characterisation data for the paper 'A fragment-based approach to targeting IMPDH from Mycobacterium tuberculosis'. NMR, LCMS, HRMS for all compounds in the paper. IC50 curves for compounds screened against IMPDH from Mtb.
Format
Adobe Acrobat Word
Keywords
NMR, LCMS, HRMS, IC50
Relationships
Publication Reference: https://doi.org/10.1021/acs.jmedchem.7b01622
Sponsorship
This work was supported by the Bill and Melinda Gates Foundation (Hit-TB) and FP7 European Project MM4TB Grant no. 260872. D.B.A was supported by a C. J. Martin Research Fellowship from the National Health and Medical Research Council of Australia (APP1072476) and the Jack Brockhoff Foundation (JBF 4186, 2016). D.B.A. and T.L.B. were also funded by a Newton Fund RCUK-CONFAP Grant awarded by The Medical Research Council and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (MR/M026302/1). V.M. and V.S. were also supported by grants from the HHMI (Senior International Research Scholars grant to V.M.), the South African Medical Research Council and the National Research Foundation.
Identifiers
This record's DOI: https://doi.org/10.17863/CAM.20512
Rights
Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International, Attribution 4.0 International
Licence URL: http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/licenses/by/4.0/