Neoplasia in Three Aye-Ayes (Daubentonia madagascariensis).
Journal of comparative pathology
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Rodriguez Barbon, A., Cowen, R., Knott, C., Hughes, K., Allinson, K., Williams, C., & Routh, A. (2018). Neoplasia in Three Aye-Ayes (Daubentonia madagascariensis).. Journal of comparative pathology, 159 16-20. https://doi.org/10.1016/j.jcpa.2017.12.008
Tumours diagnosed in three aged captive aye-aye (Daubentonia madagascariensis), held in two different institutions, are described. A cerebral glioblastoma was diagnosed based on histological and immunohistochemical findings in one of the animals following initial presentation with bilateral mydriasis, absent pupillary reflex, head tilt and ataxia. A second animal was humanely destroyed due to impaired locomotion associated with spondylosis and a post-mortem diagnosis of cholangiocarcinoma was made based on histology with further confirmation with immunohistochemical labelling for cytokeratin 7. A third aye-aye suffering from dental disease was diagnosed with an oral squamous cell carcinoma following an excisional biopsy from a non-healing wound in the lip. Due to progression of the neoplasia the animal was humanely destroyed and post-mortem examination revealed the presence on an additional unilateral phaeochromocytoma.
Animals, Strepsirhini, Neoplasms, Female, Male
External DOI: https://doi.org/10.1016/j.jcpa.2017.12.008
This record's URL: https://www.repository.cam.ac.uk/handle/1810/273657
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: http://creativecommons.org/licenses/by-nc-nd/4.0/
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