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dc.contributor.authorBraidwood, Lukeen
dc.contributor.authorQuito-Avila, Diego Fen
dc.contributor.authorCabanas, Darleneen
dc.contributor.authorBressan, Albertoen
dc.contributor.authorWangai, Anneen
dc.contributor.authorBaulcombe, Daviden
dc.date.accessioned2018-03-09T15:34:25Z
dc.date.available2018-03-09T15:34:25Z
dc.date.issued2018-01-19en
dc.identifier.issn2045-2322
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/273895
dc.description.abstractMaize chlorotic mottle virus has been rapidly spreading around the globe over the past decade. The interactions of maize chlorotic mottle virus with Potyviridae viruses causes an aggressive synergistic viral condition - maize lethal necrosis, which can cause total yield loss. Maize production in sub-Saharan Africa, where it is the most important cereal, is threatened by the arrival of maize lethal necrosis. We obtained maize chlorotic mottle virus genome sequences from across East Africa and for the first time from Ecuador and Hawaii, and constructed a phylogeny which highlights the similarity of Chinese to African isolates, and Ecuadorian to Hawaiian isolates. We used a measure of clustering, the adjusted Rand index, to extract region-specific SNPs and coding variation that can be used for diagnostics. The population genetics analysis we performed shows that the majority of sequence diversity is partitioned between populations, with diversity extremely low within China and East Africa.
dc.format.mediumElectronicen
dc.languageengen
dc.publisherNature Publishing Group
dc.rightsAttribution 4.0 International*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectGammaherpesvirinaeen
dc.subjectComputational Biologyen
dc.subjectPhylogenyen
dc.subjectPlant Diseasesen
dc.subjectBase Sequenceen
dc.subjectGenotypeen
dc.subjectPolymorphism, Single Nucleotideen
dc.subjectGenome, Viralen
dc.subjectGenetic Variationen
dc.subjectHigh-Throughput Nucleotide Sequencingen
dc.subjectGeography, Medicalen
dc.titleMaize chlorotic mottle virus exhibits low divergence between differentiated regional sub-populations.en
dc.typeArticle
prism.issueIdentifier1en
prism.publicationDate2018en
prism.publicationNameScientific reportsen
prism.startingPage1173
prism.volume8en
dc.identifier.doi10.17863/CAM.20969
dcterms.dateAccepted2017-12-29en
rioxxterms.versionofrecord10.1038/s41598-018-19607-4en
rioxxterms.versionVoR*
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2018-01-19en
dc.contributor.orcidBraidwood, Luke [0000-0002-0233-3605]
dc.contributor.orcidBaulcombe, David [0000-0003-0780-6878]
dc.identifier.eissn2045-2322
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idBBSRC (1344406)
cam.orpheus.successThu Jan 30 13:00:28 GMT 2020 - The item has an open VoR version.*
rioxxterms.freetoread.startdate2100-01-01


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International