Testicular cancer in 2017: Sequencing advances understanding.
Nature reviews. Urology
MetadataShow full item record
Murray, M., & Turnbull, C. (2018). Testicular cancer in 2017: Sequencing advances understanding.. Nature reviews. Urology, 15 (2), 79-80. https://doi.org/10.1038/nrurol.2017.209
Our biological understanding of TGCTs has been improved using sequencing, and molecular profiles associated with the genomic evolution and development of cisplatin resistance have been identified. The genomics of variants underpinning TGCT predisposition is being delineated. Studies of circulating microRNAs have demonstrated their potential for noninvasive diagnosis and disease monitoring.
Humans, Neoplasms, Germ Cell and Embryonal, Testicular Neoplasms, Genetic Predisposition to Disease, MicroRNAs, Drug Resistance, Neoplasm, Male, Genetic Variation, Genome-Wide Association Study, Biomarkers, Tumor, Whole Exome Sequencing
Isaac Newton Trust (1540 (f))
St Baldrick's Foundation (via Dana-Farber Cancer Institute) (2015-0743)
External DOI: https://doi.org/10.1038/nrurol.2017.209
This record's URL: https://www.repository.cam.ac.uk/handle/1810/273922