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dc.contributor.authorRichards, Garethen
dc.contributor.authorKlimek, Magdalenaen
dc.contributor.authorJasienska, Grazynaen
dc.contributor.authorMarcinkowska, Urszula Men
dc.date.accessioned2018-03-29T14:16:24Z
dc.date.available2018-03-29T14:16:24Z
dc.date.issued2018-02en
dc.identifier.issn0378-3782
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/274518
dc.description.abstract© 2017 Elsevier B.V. Background Digit ratio (2D:4D) is used by researchers as an indicator of prenatal sex hormone exposure. Two previous studies have examined associations between 2D:4D and circulating sex steroid concentrations across the menstrual cycle in adult females. One reported that digit ratio correlated positively with oestradiol levels, whereas the other found no such effect; neither observed significant associations with progesterone. Aims To examine associations between 2D:4D, as well as asymmetry (i.e. right minus left 2D:4D), and circulating sex steroids across the menstrual cycle. Study design Correlational. Subjects 32 naturally cycling adult females from rural southern Poland. Outcome measures Salivary oestradiol, progesterone, testosterone, and testosterone to oestradiol ratio (T:O) measured during the follicular, peri-ovulatory, and luteal phases. Average levels across the cycle were also examined. Results and conclusions Asymmetry in digit ratio correlated positively with oestradiol at each phase, as well as with average levels across the cycle. Each association, other than that relating to average levels, remained statistically significant after a range of covariates had been controlled for. No other significant correlations were observed between digit ratio variables and circulating hormone levels. Our results might suggest that low exposure to androgens and/or high exposure to oestrogens during gestation is a predictor of high oestradiol levels in naturally cycling females of reproductive age. However, considering that it was asymmetry in digit ratio, and not either right or left 2D:4D, that was a significant predictor, it is also possible that these effects reflect more general associations between bilateral asymmetry and circulating oestradiol levels.
dc.format.mediumPrint-Electronicen
dc.languageengen
dc.subjectFingersen
dc.subjectHumansen
dc.subjectTestosteroneen
dc.subjectEstradiolen
dc.subjectProgesteroneen
dc.subjectMenstrual Cycleen
dc.subjectAdulten
dc.subjectFemaleen
dc.titleDigit ratio (2D:4D) and circulating testosterone, oestradiol, and progesterone levels across the menstrual cycle.en
dc.typeArticle
prism.endingPage73
prism.publicationDate2018en
prism.publicationNameEarly human developmenten
prism.startingPage68
prism.volume117en
dc.identifier.doi10.17863/CAM.21636
dcterms.dateAccepted2017-12-05en
rioxxterms.versionofrecord10.1016/j.earlhumdev.2017.12.006en
rioxxterms.versionAM*
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/en
rioxxterms.licenseref.startdate2018-02en
dc.contributor.orcidRichards, Gareth [0000-0003-0233-0153]
dc.contributor.orcidJasienska, Grazyna [0000-0001-8716-6342]
dc.contributor.orcidMarcinkowska, Urszula M [0000-0002-6851-4513]
dc.identifier.eissn1872-6232
rioxxterms.typeJournal Article/Reviewen
rioxxterms.freetoread.startdate2019-01-08


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